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530409

Sigma-Aldrich

Propargyl bromide solution

80 wt. % in xylene

Sinônimo(s):

3-Bromo-1-propyne

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About This Item

Fórmula linear:
HC≡CCH2Br
Número CAS:
106-96-7
Peso molecular:
118.96
Beilstein:
605309
Número MDL:
MFCD00000241
Código UNSPSC:
12352100
ID de substância PubChem:
24877746
NACRES:
NA.22

concentração

80 wt. % in xylene

índice de refração

n20/D 1.494

pb

97 °C

densidade

1.34 g/mL at 25 °C

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

BrCC#C

InChI

1S/C3H3Br/c1-2-3-4/h1H,3H2

chave InChI

YORCIIVHUBAYBQ-UHFFFAOYSA-N

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Descrição geral

The product is an 80wt.% solution of propargyl bromide (3-bromo-1-propyne) in xylene.

Aplicação

Propargyl bromide solution (80wt.% solution in xylene) may be used in the preparation of dimethyl 5-hydroxyisophthalate propargyl ether.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Oral - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT RE 2 Inhalation - STOT SE 3

Órgãos-alvo

Central nervous system,Liver,Kidney, Respiratory system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

45.0 °F - closed cup

Ponto de fulgor (°C)

7.22 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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International immunopharmacology, 29(1), 105-109 (2015-06-03)
The involvement of muscarinic receptors in cancer has been reported. Recently we have demonstrated that the activation of M2 muscarinic receptors, through arecaidine propargyl ester, arrests cell proliferation and induces apoptosis in primary and established glioblastoma cell lines. Considering the
Maria Di Bari et al.
Neurochemistry international, 90, 261-270 (2015-10-13)
Glioblastomas are the most common brain tumors in humans. Previously, we demonstrated that the muscarinic receptor agonist, arecaidine propargyl ester, via M2 receptors, inhibits cell proliferation in a time and dose-dependent manner and induces a severe apoptosis in human U251
Jong Hwan Kwak et al.
Biomaterials, 61, 52-60 (2015-05-23)
We studied the blood-brain barrier (BBB) permeability and intracellular localization of a fluorescein isothiocyanate (FITC)-labeled dieckol (1) and a rhodamine B-labeled dieckol (7), for exploring the possible therapeutic application of fluorone-labeled dieckols in neurodegenerative diseases. Both compounds (1 &7) were
Abdelaziz Al Ouahabi et al.
Journal of the American Chemical Society, 137(16), 5629-5635 (2015-04-09)
Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrityloxy-propyl) diisopropylphosphoramidite (0), 2-cyanoethyl (3-dimethoxytrityloxy-2,2-dimethyl-propyl) diisopropylphosphoramidite (1), and 2-cyanoethyl (3-dimethoxytrityloxy-2,2-dipropargyl-propyl) diisopropylphosphoramidite (1'). Phosphoramidite coupling steps allowed rapid synthesis

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