394963

N,N-Dimethylformamide dimethyl acetal

derivatization grade (GC derivatization), LiChropur^™

• Sinônimo(s): 1,1-Dimethoxy-N,N-dimethylmethylamine, 1,1-Dimethoxytrimethylamine
• Fórmula linear: (CH₃)₂NCH(OCH₃)₂
• Número CAS: 4637-24-5
• Peso molecular: 119.16
• Beilstein: 506020
• Número CE: 225-063-3
• Número MDL: MFCD00008482
• Código UNSPSC: 23151817
• ID de substância PubChem: 24864631
• NACRES: NA.22

Propriedades

• grau: derivatization grade (GC derivatization)
• Nível de qualidade: 100
• Ensaio: >95%
• Formulário: liquid
• qualidade: LiChropur^™
• adequação da reação: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• técnica(s): gas chromatography (GC): suitable
• índice de refração: n20/D 1.396 (lit.)
• p.e.: 102-103 °C/720 mmHg (lit.)
• densidade: 0.897 g/mL at 25 °C (lit.)
• cadeia de caracteres SMILES: COC(OC)N(C)C
• InChI: 1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3
• chave InChI: ZSXGLVDWWRXATF-UHFFFAOYSA-N

Descrição

Descrição geral

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.[1]

Aplicação

It may be used in methylation of heterocyclic compounds which contains SH, NH, OH groups such as benzimidazole, naphth[2,3-c]imidazole, imidazo[4,5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo[4,3-b]pyridazine.[2] It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation.[3]

Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid.

Used in the preparation of formamidine derivatives,[4][5] which are synthetic intermediates.[6]

Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.[7]

Outras notas

Reagent for n-dimethylaminomethylene and methyl esters.

Informações legais

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS02,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H225,H317,H318,H332
• Declarações de precaução: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Sens. 1
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 42.8 °F
• Ponto de fulgor (°C): 6 °C
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter