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38534

Sigma-Aldrich

Polylactic acid

Mw ~60,000

Sinônimo(s):

Poly(2-hydroxypropionic acid)

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About This Item

Número CAS:
26100-51-6
Número MDL:
MFCD00081867
Código UNSPSC:
12162002
NACRES:
NA.23

forma

solid

prazo de validade

limited shelf life, expiry date on the label

peso molecular

Mn ~30,000
Mw ~60,000

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

chave InChI

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

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Descrição geral

Polylactic acid(PLA) is a biodegradable polyester synthesized from lactic acid monomer via ring opening polymerization. Owing to its excellent thermal, mechanical and barrier properties, it is widely used in the field of tissue engineering, drug delivery, and orthopedic devices.

Aplicação

Polylactic acid can be used to prepare tubular scaffolds via the electrospinning method. These scaffolds are applicable in vascular tissue engineering.

It can be used to prepare PLA/polyvinyl alcohol wound dressing membrane through electrospinning and coating method. The coating of PLA improves the mechanical strength of nanofiber and acts as a protective layer to control the release of drug to the wound site.

It can also be used to synthesize free-standing, flexible ultra-thin PLA nanofilms which can act as a matrix for adhesion, spreading, and proliferation of skeletal muscle cells.

Características e benefícios

  • Biocompatibility
  • Lower toxicity
  • Low cost
  • Better encapsulation

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Polyglycolide inherent viscosity 1.4dL/g

Sigma-Aldrich

457620

Polyglycolide

Poly(L-lactide) viscosity ~2.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

81273

Poly(L-lactide)

Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

R M Felfel et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1914-1924 (2013-03-19)
Fibre reinforced composites have recently received much attention as potential bone fracture fixation applications. Bioresorbable composites based on poly lactic acid (PLA) and phosphate based glass fibre were investigated according to ion release, degradation, biocompatibility and mechanical retention profiles. The
Paul S Rosen et al.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 34(1), 34-38 (2013-04-05)
This retrospective case series reports on the use of a polylactic acid barrier that was left exposed in the process of socket preparation for the placement of dental implants. A retrospective chart review found 43 patients with 48 extraction sockets
Dah Hee Kim et al.
Carbohydrate polymers, 92(2), 1006-1011 (2013-02-13)
The purpose of this study is to evaluate the rheological and thermal properties of poly(l-lactic acid) (PLA) composites incorporated with microcrystalline cellulose (MCC) and lignin. The MCC/lignin/PLA composites were fabricated through direct melt compounding. In particular, the effect regarding the
Huan Zhou et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2302-2310 (2013-03-19)
Fibrous bionanocomposites consisting of amorphous magnesium phosphate (AMP) nanospheres and polylactic acid (PLA) were fabricated by electrospinning. There are two important signatures of this paper. First, AMP, as an alternative to well-known calcium phosphate (CaP) materials, is added to PLA
L Pearce McCarty et al.
The Journal of bone and joint surgery. American volume, 95(6), 507-511 (2013-02-15)
A variety of complications associated with the use of poly-L-lactic acid (PLLA) implants, including anchor failure, osteolysis, glenohumeral synovitis, and chondrolysis, have been reported in patients in whom these implants were utilized for labral applications. We report on a large
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