371130

1,4-Diisocyanatobutane

97.0%

• Sinônimo(s): Tetramethylene diisocyanate
• Fórmula linear: OCN(CH₂)₄NCO
• Número CAS: 4538-37-8
• Peso molecular: 140.14
• Beilstein: 1756894
• Número MDL: MFCD00075559
• Código UNSPSC: 12162002
• ID de substância PubChem: 24863093
• NACRES: NA.23

Propriedades

• Ensaio: 97.0%
• Formulário: liquid
• p.e.: 102-104 °C/14 mmHg (lit.)
• densidade: 1.105 g/mL at 25 °C (lit.)
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=C=NCCCCN=C=O
• InChI: 1S/C6H8N2O2/c9-5-7-3-1-2-4-8-6-10/h1-4H2
• chave InChI: OVBFMUAFNIIQAL-UHFFFAOYSA-N

Descrição

Descrição geral

1,4-Diisocyanatobutane is a highly reactive compound with two isocyanate (-NCO) groups separated by a butane chain. It can undergo reactions such as urethane formation, crosslinking, and chain extension. It is widely used as a building block to synthesize polyurethane-based materials with excellent flexibility, impact resistance, and mechanical properties, making them useful in tissue engineering, contact lenses, biocompatible coatings, adhesives, foams, elastomers, and sealants.

Aplicação

1,4-Diisocyanatobutanecan be used in the following fields:

Tissue engineering -As a precursor to synthesize polyurethane composites which can be used as 3D scaffolds for tissue engineering,

Contact lenses- As a cross-linking agent to prepare inorganic-organic hydrogel contact lenses for high refractive index ocular refractive correction biomaterial,

Controlled drug delivery- As a chain extender to synthesize segmented polyurethanes for redox-sensitive controlled drug release systems.

Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302 + H312 + H332,H315,H317,H319,H334,H335
• Declarações de precaução: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 222.8 °F - closed cup
• Ponto de fulgor (°C): 106 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter