270148

Methyl (R)-(−)-3-hydroxy-2-methylpropionate

99%

• Sinônimo(s): (−)-Methyl D-β-hydroxyisobutyrate, (R)-(−)-3-Hydroxy-2-methylpropionic acid methyl ester
• Fórmula linear: HOCH₂CH(CH₃)CO₂CH₃
• Número CAS: 72657-23-9
• Peso molecular: 118.13
• Beilstein: 3587507
• Número MDL: MFCD00063450
• Código UNSPSC: 12352108
• ID de substância PubChem: 24856357
• NACRES: NA.22

Propriedades

• Ensaio: 99%
• Formulário: liquid
• atividade óptica: [α]19/D −26°, c = 4 in methanol
• pureza óptica: ee: 99% (GLC)
• índice de refração: n20/D 1.425 (lit.)
• p.e.: 76-77 °C/12 mmHg (lit.)
• densidade: 1.066 g/mL at 25 °C (lit.)
• grupo funcional: ester; hydroxyl
• cadeia de caracteres SMILES: COC(=O)[C@H](C)CO
• InChI: 1S/C5H10O3/c1-4(3-6)5(7)8-2/h4,6H,3H2,1-2H3/t4-/m1/s1
• chave InChI: ATCCIZURPPEVIZ-SCSAIBSYSA-N

Descrição

Aplicação

Methyl (R)-(-)-3-hydroxy-2-methylpropionate may be used in the preparation of (S)-(4-benzyloxy-3-methylbut-1-ynyl)triethylsilane.[1] It may also be used as a starting material in the total synthesis of (-)-discodermolide[2], (-)-stemoamide[3] and (-)-stemospironine.[4]

The (R)- and (S)-isomers are bifunctional building blocks for the synthesis of a wide variety of optically active molecules.[5][6][7]

Informações de segurança

• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 176.0 °F - closed cup
• Ponto de fulgor (°C): 80 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter