Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

145505

Sigma-Aldrich

αÁcido α-ciano-4-hidroxicinâmico

97%

Sinônimo(s):

αα-CCA, αα-CHCA, αα-ciano, 4-HCCA, ACCA

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula linear:
HOC6H4CH=C(CN)CO2H
Número CAS:
28166-41-8
Peso molecular:
189.17
Beilstein:
3271427
Número CE:
248-879-1
Número MDL:
MFCD00004204
Código UNSPSC:
12352100
ID de substância PubChem:
24848731
NACRES:
NA.22

Ensaio

97%

forma

powder

pf

245-250 °C (lit.)

solubilidade

methanol: soluble 50 mg/mL, clear to slightly hazy, light yellow to yellow

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

chave InChI

AFVLVVWMAFSXCK-VMPITWQZSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.

Aplicação

α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H317

Classificações de perigo

Skin Sens. 1B

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 4

1 of 4

Sinapic acid matrix substance for MALDI-MS, ≥99.0% (T)

Supelco

85429

Sinapic acid

Potassium tetrachloroplatinate(II) 98%

Sigma-Aldrich

206075

Potassium tetrachloroplatinate(II)

1,5-Diaminonaphthalene 97%

Sigma-Aldrich

D21200

1,5-Diaminonaphthalene

2,5-Dihydroxybenzoic acid matrix substance for MALDI-MS, >99.0% (HPLC)

Supelco

85707

2,5-Dihydroxybenzoic acid

S D Patterson et al.
Analytical chemistry, 66(21), 3727-3732 (1994-11-01)
During the analysis of an Asp-N digest of a recombinant hematopoietic growth factor by matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS), we observed pseudomolecular ions corresponding to reduced forms of peptides known to be present only in single disulfide linkages.
G M Hathaway
BioTechniques, 17(1), 150-155 (1994-07-01)
A commercially available, matrix-assisted, laser desorption/ionization (MALDI), time-of-flight mass spectrometer has been used for the successful characterization of picomole quantities of modified deoxyoligonucleotides. The procedure was found to be applicable to the analysis of a variety of modified synthetic structures
Claudia Ryppa et al.
International journal of pharmaceutics, 368(1-2), 89-97 (2008-11-11)
The alpha(v)beta(3) integrin is overexpressed on proliferating endothelial cells such as those present in growing tumors as well as on tumor cells of various origins. Tumor-induced angiogenesis can be inhibited in vivo by antagonizing the alpha(v)beta(3) integrin with small peptides
Yusaku Hioki et al.
Journal of mass spectrometry : JMS, 48(11), 1217-1223 (2013-11-22)
We describe here an optimization study of the sample preparation conditions for sensitive detection of peptides by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Among many factors in the conditions, we varied the percent acetonitrile in the peptide solution, the percent
Encapsulation of α-cyano-4-hydroxycinnamic acid into a NaY zeolite.
Vilaca N, et al.
J. Mater. Sci., 46(23), 7511-7516 (2011)
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica