61743

N-Lauroylsarcosine sodium salt

BioUltra, for molecular biology, ≥99.0% (HPLC)

• Synonyme(s) : N-lauroylsarcosine sodium salt, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL
• Formule linéaire : CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• Numéro CAS: 137-16-6
• Poids moléculaire : 293.38
• Beilstein: 5322974
• Numéro CE : 205-281-5
• Numéro MDL: MFCD00042728
• Code UNSPSC : 12161900
• ID de substance PubChem : 57651862
• Nomenclature NACRES : NA.25

Propriétés

• Qualité: for molecular biology
• Niveau de qualité: 200
• Description: anionic
• Gamme de produits: BioUltra
• Essai: ≥99.0% (HPLC)
• Forme: powder
• Poids mol.: micellar avg mol wt 600; average mol wt 600
• Nombre d'agrégation: 2
• Impuretés: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• Perte: ≤1% loss on drying, 110 °C
• pH: 7.0-9.0 (25 °C, 1 M in H₂O)
• CMC: 14.6 mM (20-25°C)
• Solubilité: H₂O: 1 M at 20 °C, clear, colorless
• Traces d'anions: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorption UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.06
• Chaîne SMILES: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• Application(s): sample preservation
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
• Clé InChI: KSAVQLQVUXSOCR-UHFFFAOYSA-M

Description

Description générale

The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs).[1]

Application

N-Lauroylsarcosine sodium salt has been used as a component:

• of nuclease stop mix, embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
• of proteinase K solution for the heat denaturation of genomic DNA
• of 10% (w/v) sarcosyl/0.5 M ethylenediaminetetraacetic acid (EDTA) solution to prepare EDTA-sarcosyl-proteinase (ESP) buffer
• in the hybridization buffer for in situ hybridization histochemistry[2]
• in the embryo extract buffer to dissociate nonspecifically bound proteins from chromatin[3]
• in proteinase K solution to inactivate the enzymes[4]

Autres remarques

Anionic surfactant.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H315,H318,H330
• Conseils de prudence: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 512.6 °F - closed cup
• Point d'éclair (°C): 267 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)