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47673

Sigma-Aldrich

Formaldéhyde solution

tested according to Ph. Eur.

Synonyme(s) :

Formol

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About This Item

Formule linéaire :
HCHO
Numéro CAS:
50-00-0
Poids moléculaire :
30.03
Numéro Beilstein :
1209228
Numéro MDL:
MFCD00003274
Code UNSPSC :
12352114
ID de substance PubChem :
329757334
Nomenclature NACRES :
NA.25

Agence

USP/NF
tested according to Ph. Eur.

Niveau de qualité

200

Densité de vapeur

1.03 (vs air)

Pression de vapeur

52 mmHg ( 37 °C)

Forme

liquid

Température d'inflammation spontanée

572 °F

Contient

9.0-15.0 % (v/v) methanol as stabilizer

Concentration

25-50%

Solubilité

water: soluble

Densité

1.09 g/mL at 25 °C (lit.)

Adéquation

suitable for manufacturing use (Laboratory chemicals)

Chaîne SMILES 

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

Clé InChI

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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Application

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Actions biochimiques/physiologiques

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Attention

may become turbid on storage

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Organes cibles

Eyes,Central nervous system, Respiratory system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

133.0 °F - closed cup

Point d'éclair (°C)

56.11 °C - closed cup

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
BCCL7378
BCCL8065
BCCL5543
BCCK8902
BCCL0858

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

J L Wilson et al.
Journal of immunology (Baltimore, Md. : 1950), 163(12), 6365-6370 (1999-12-10)
NK cells have the capacity to spontaneously kill tumor cell lines, in particular cell lines of hemopoietic origin. In contrast, they do not generally kill nontransformed autologous cells. However, here we demonstrate that short-term activated polyclonal human NK cells, as
O Merk et al.
Environmental and molecular mutagenesis, 32(3), 260-268 (1998-11-14)
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used
Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehyde.
H Boedtker
Journal of molecular biology, 35(1), 61-70 (1968-07-14)
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
Stephanie Belloc et al.
Fertility and sterility, 101(6), 1588-1593 (2014-04-03)
To evaluate sperm DNA fragmentation in normozoospermic male partners of couples undergoing infertility evaluation. Retrospective cohort study. Clinical andrology laboratory. A total of 1,974 consecutive normozoospermic men selected from a larger cohort of 4,345 consecutive, nonazoospermic men presenting for infertility
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