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09569

Supelco

Span® 80

greener alternative

suitable for GC

Synonyme(s) :

Sorbitan monooleate, Span® 80

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About This Item

Formule empirique (notation de Hill):
C24H44O6
Numéro CAS:
1338-43-8
Poids moléculaire :
428.60
Numéro Beilstein :
8172514
Numéro CE :
215-665-4
Numéro MDL:
MFCD00080948
Code UNSPSC :
12000000
ID de substance PubChem :
329748773
Nomenclature NACRES :
NA.21

Description

non-ionic

Niveau de qualité

100

Poids mol.

428.60 g/mol

Caractéristiques du produit alternatif plus écologique

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Technique(s)

LPLC: suitable
gas chromatography (GC): suitable
protein quantification: suitable

Indice de réfraction

n20/D 1.48 (lit.)

HLB

4.6±0.1

Densité

0.99 g/mL at 20 °C
0.986 g/mL at 25 °C (lit.)

Autre catégorie plus écologique

Aligned,

Chaîne SMILES 

[H][C@@](O)(COC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

Clé InChI

NWGKJDSIEKMTRX-AAZCQSIUSA-N

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Catégories apparentées

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is biodegradable surfactant, thus aligns with "Use of Renewable Feedstocks" and "Design for Degradation" principles of Green Chemistry, and belongs to "12 principles aligned" category of our greener alternatives.

Application

A non-ionic surfactant that can be used to form oil-in-water emulsions and in combination with low HLB surfactants can form water-in-oil emulsions. EPA approved oil spill dispersant.

Informations légales

Span is a registered trademark of Croda International PLC

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCM0986
BCCK8479
BCCJ9835
BCCG6479
BCCD4633

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Geneviève LeBel et al.
Applied and environmental microbiology, 80(17), 5484-5492 (2014-06-29)
Streptococcus suis serotype 2 is known to cause severe infections (meningitis, endocarditis, and septicemia) in pigs and is considered an emerging zoonotic agent. Antibiotics have long been used in the swine industry for disease treatment/prevention and growth promoters. This pattern
Faiyaz Shakeel et al.
Drug development and industrial pharmacy, 40(9), 1240-1245 (2013-07-11)
Abstract For the development of an effective self-nanoemulsifying drug delivery system (SNEDDS) of poorly soluble drugs, the knowledge of the solubility in its oil phase and SNEDDS are one of the most important factors to avoid possibility of drug to
Xiazhong Ren et al.
International journal of pharmaceutics, 431(1-2), 130-137 (2012-05-03)
This study is the first to investigate and demonstrate the potential of microemulsions (MEs) for sustained release parenteral drug delivery, due to phase transition behavior in aqueous environments. Phase diagrams were constructed with Miglyol 812N oil and a blend of
Chenguang Zhou et al.
Molecular pharmaceutics, 9(2), 201-210 (2011-12-14)
Nonionic surfactant vesicles, or SPANosomes (SPs), comprised of cationic lipid and sorbitan monooleate (Span 80) were synthesized and evaluated as small interfering RNA (siRNA) vectors. The SPs had a mean diameter of less than 100 nm and exhibited excellent colloidal
Hoang Hirschberg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(1-2), 1-7 (2012-02-15)
In the search for an optimal approach for the transcutaneous immunization (TCI) of hepatitis B surface antigen (HBsAg), two vesicle formulations, L595 vesicles (composed of sucrose-laurate ester and octaoxyethylene-laurate ester) and sPC vesicles (composed of soybean-phosphatidylcholine and Span-80) were prepared
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