SML1087

Sumanirole maleate

≥98% (HPLC)

• Synonym(e): (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, CID 9818479 maleate, PNU-95,666 maleate
• Empirische Formel (Hill-System): C₁₁H₁₃N₃O · C₄H₄O₄
• CAS-Nummer: 179386-44-8
• Molekulargewicht: 319.31
• MDL-Nummer: MFCD09832637
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825464
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D -22 to -32°, c = 1 in H₂O
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 10 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=C\C(O)=O
• InChI: 1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1
• InChIKey: VOJRMYBBPKNLLI-ORHWHDKWSA-N

Beschreibung

Anwendung

Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats.

Biochem./physiol. Wirkung

Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.

Leistungsmerkmale und Vorteile

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable