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SML0463

Sigma-Aldrich

BPD

≥98% (HPLC)

Synonym(e):

3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione

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About This Item

Empirische Formel (Hill-System):
C17H10O5
CAS-Nummer:
213481-12-0
Molekulargewicht:
294.26
MDL-Nummer:
MFCD22666591
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329824741

Assay

≥98% (HPLC)

Form

powder

Lagerbedingungen

desiccated

Farbe

white to beige

Löslichkeit

DMSO: 15 mg/mL (clear solution)

Lagertemp.

−20°C

SMILES String

O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4

InChI

1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2

InChIKey

IMHGOAWBSJVILI-UHFFFAOYSA-N

Biochem./physiol. Wirkung

BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.
BPD inhibits LPS-induced NF-kB signaling; COX-2 inhibitor.

Leistungsmerkmale und Vorteile

This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

H-Sätze

H302,H400

P-Sätze

P273

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
082M4618V

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Sebastian Euler et al.
Frontiers in psychology, 9, 824-824 (2018-06-19)
Interpersonal sensitivity, particularly threat of potential exclusion, is a critical condition in borderline personality disorder (BPD) which impairs patients' social adjustment. Current evidence-based treatments include group components, such as mentalization-based group therapy (MBT-G), in order to improve interpersonal functioning. These
Jennifer Sophie Landry et al.
Annals of the American Thoracic Society, 13(1), 17-24 (2015-11-03)
Bronchopulmonary dysplasia and the long-term consequences of prematurity are underrecognized entities, unfamiliar to adult clinicians. Well described by the pediatric community, these young adults are joining the ranks of a growing population of adults with chronic lung disease. To describe
Anna Karin Edstedt Bonamy et al.
Archives of disease in childhood. Fetal and neonatal edition, 104(1), F36-F45 (2018-01-22)
To investigate the variation in severe neonatal morbidity among very preterm (VPT) infants across European regions and whether morbidity rates are higher in regions with low compared with high mortality rates. Area-based cohort study of all births before 32 weeks
Johanna Köhling et al.
Journal of personality disorders, 30(6), 776-795 (2015-12-02)
The quality of depression in borderline personality disorder (BPD) was reported to differ from that in patients with major depressive disorder (MDD) only. However, little is known about affect dynamics in "borderline-depression." The authors assessed affective instability and reactivity in
Graciela Sotelo et al.
BMC evolutionary biology, 20(1), 23-23 (2020-02-11)
The flat periwinkles, Littorina fabalis and L. obtusata, are two sister species widely distributed throughout the Northern Atlantic shores with high potential to inform us about the process of ecological speciation in the intertidal. However, whether gene flow has occurred
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