SCP0051
[Glp3]-Amyloid β 3-42 human
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1 MG
€ 528,00
€ 528,00
Versand in der Regel in 2 Wochen.
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1 MG
€ 528,00
About This Item
Empirische Formel (Hill-System):
C196H299N53O55S1
Molekulargewicht:
4309.86
UNSPSC-Code:
12352209
NACRES:
NA.32
€ 528,00
Versand in der Regel in 2 Wochen.
Empfohlene Produkte
Assay
≥95% (HPLC)
Form
lyophilized
Zusammensetzung
Peptide Content, ≥75%
Lagerbedingungen
protect from light
Lagertemp.
−20°C
Amino Acid Sequence
Glp-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Anwendung
Amyloid β (Aβ) refers to peptides derived from Amyloid precursor protein that vary in length from 36-43 amino acids. Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer′s disease and neurodegeneration.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Gawain McColl et al.
The Journal of biological chemistry, 284(34), 22697-22702 (2009-07-04)
Transgenic expression of human amyloid beta (A beta) peptide in body wall muscle cells of Caenorhabditis elegans has been used to better understand aspects of Alzheimer disease (AD). In human aging and AD, A beta undergoes post-translational changes including covalent
Oliver Wirths et al.
Acta neuropathologica, 118(4), 487-496 (2009-06-24)
It is well established that only a fraction of Abeta peptides in the brain of Alzheimer's disease (AD) patients start with N-terminal aspartate (Abeta(1D)) which is generated by proteolytic processing of amyloid precursor protein (APP) by BACE. N-terminally truncated and
Heinke Schieb et al.
The Journal of biological chemistry, 286(39), 33747-33758 (2011-07-29)
In this study, we report a detailed analysis of the different variants of amyloid-β (Aβ) peptides in the brains and the cerebrospinal fluid from APP23 transgenic mice, expressing amyloid precursor protein with the Swedish familial Alzheimer disease mutation, at different
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