Fortfahren mit
SAE0003
4-Hydroxyphenylpyruvate Dioxygenase from Streptomyces avermitilis
recombinant, expressed in E. coli
Anmelden zur Ansicht der Organisations- und Vertragspreise.
Größe auswählen
Ansicht ändern
| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 332,00 |
Über diesen Artikel
Specific activity:
≥5 U/mg
Recombinant:
expressed in E. coli
€ 332,00
Warenkorb auf Verfügbarkeit prüfen
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhaltenrecombinant
expressed in E. coli
Quality Segment
form
liquid
specific activity
≥5 U/mg
mol wt
~41.8 kDa
shipped in
dry ice
storage temp.
−70°C
General description
4-Hydroxyphenylpyruvate Dioxygenase (4-HPPD) is a key enzyme in the catabolism of tyrosine and phenylalanine. 4-HPPD catalyzes the synthesis of homogenistate (2,5-dihydroxyphenylacetate) from ρ-hydroxyphenylpyruvate and molecular oxygen. 4-HPPD also catalyzes the conversion of α-ketoisocaproate to Β-hydroxyisovalerate. 4-HPPD requires Fe2+ as an essential cofactor.
Rat 4-HPPD has a minimum of 80% homology with human 4-HPPD. Rat 4-HPPD is expressed abundantly in hepatocytes. It is also expressed in kidney, particularly in epithelial cells of the proximal tubules and the distant tubules. 4-HPPD has been identified as a potential biomarker of drug-induced liver injury in rat studies.
Rat 4-HPPD has a minimum of 80% homology with human 4-HPPD. Rat 4-HPPD is expressed abundantly in hepatocytes. It is also expressed in kidney, particularly in epithelial cells of the proximal tubules and the distant tubules. 4-HPPD has been identified as a potential biomarker of drug-induced liver injury in rat studies.
Other Notes
One unit will oxidize 1 μmole of molecular oxygen per minute at pH 7.0, 25 °C, in the presence of 4-hydroxyphenylpyruvate.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description recombinant, expressed in E. coli | description lyophilized powder, ≥3 units/mg solid | description ≥50,000 units/mL, buffered aqueous glycerol solution | description recombinant, expressed in E. coli, lyophilized powder, ≥5.0 units/mg solid |
| specific activity ≥5 U/mg | specific activity ≥3 units/mg solid | specific activity ≥50,000 units/mL | specific activity ≥5.0 units/mg solid |
| form liquid | form lyophilized powder | form buffered aqueous glycerol solution | form lyophilized powder |
| recombinant expressed in E. coli | recombinant - | recombinant - | recombinant expressed in E. coli |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in - |
| mol wt ~41.8 kDa | mol wt ~700 kDa | mol wt ~60 kDa | mol wt - |
| storage temp. −70°C | storage temp. −20°C | storage temp. −70°C | storage temp. 2-8°C |
Lagerklasse
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.