As reported in the 'DESCRIPTION' section of the product page, Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. This product has not been further characterized.
Fortfahren mit
S1006
Sulfatides from bovine brain
≥97% (TLC), powder
Synonym(e):
Cerebroside sulfate
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 463,00 |
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 860,00 |
50 mg | Warenkorb auf Verfügbarkeit prüfen | € 2.230,00 |
Über diesen Artikel
UNSPSC Code:
12352200
NACRES:
NA.77
Technischer Dienst
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Unterstützung erhaltenGeneral description
Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. It is localized in myelin sheath and comprises approximately 4% of total myelin lipid in brain.
Sulfatideis a glycospingolipid and plays an essential role in host-pathogen recognition,β-cell function, infection, haemostasis/thrombosis, protein trafficking, cellgrowth, cell adhesion, neuronal plasticity, cell morphogenesis, and signaltransduction. It is found on the surface of the blood cells such asplatelets, leukocytes, and erythrocytes. Sulfatides are also found in the serumas glycosphingolipids in lipoproteins. It is made up of glycan part, a hydrophobic part, 3-O-sulfated galactose, and ceramide, which in turn is composed of a sphingosine base and a fatty acid. It is an important component forthe maintenance of the myelin sheath andproper formation of the axo-glial junctions. Variations in the production ofsulfatides are associated with various human diseases like cancer andimmunological disorders. Alterations in the sulfatide metabolism lead to synapticdysfunction, neurological decline, inflammation, and myelin deterioration.
Application
Sulfatides has been used in:
- enzyme linked immunosorbent assay (ELISA) in human plasma samples
- thin layer chromatography in myelin membranes
- in sulfatide binding assay of properdin
Biochem/physiol Actions
Sulfatides play a key role in physiological processes of nervous system, immune system and in insulin secretion. Anomalies in sulfatides catabolism in lysosome is implicated in late infantile metachromatic leukodystrophy. High levels of sulfatides is also observed in ovarian cancer. Sulfatides contribute to the pathogenesis of chronic inflammatory diseases of the central nervous system.
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Dieser Artikel | |||
|---|---|---|---|
| description - | description ~95%, lyophilized powder | description ≥97% (TLC) | description Avanti Research™ - A Croda Brand |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hi, Do you have any information about the sulfatide composition/profile of “Sulfatide from bovine brain (S1006)”.
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Helpful?
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