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I0383

Sigma-Aldrich

Isobutyryl coenzyme A lithium salt

≥85%

Synonym(e):

2-Methylpropanoyl-CoA, IB-CoA

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About This Item

Empirische Formel (Hill-System):
C25H42N7O17P3S · xLi+
CAS-Nummer:
103404-95-1
Molekulargewicht:
837.62 (free acid basis)
MDL-Nummer:
MFCD00079368
UNSPSC-Code:
41106305
PubChem Substanz-ID:
24895902
NACRES:
NA.51

Assay

≥85%

Lagertemp.

−20°C

SMILES String

[Li].CC(C)C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)n2cnc3c(N)ncnc23

InChI

1S/C25H42N7O17P3S.Li.H/c1-13(2)24(37)53-8-7-27-15(33)5-6-28-22(36)19(35)25(3,4)10-46-52(43,44)49-51(41,42)45-9-14-18(48-50(38,39)40)17(34)23(47-14)32-12-31-16-20(26)29-11-30-21(16)32;;/h11-14,17-19,23,34-35H,5-10H2,1-4H3,(H,27,33)(H,28,36)(H,41,42)(H,43,44)(H2,26,29,30)(H2,38,39,40);;

InChIKey

XOJGPZXPXDNYHG-UHFFFAOYSA-N

Verwandte Kategorien

Biochem./physiol. Wirkung

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Isobutyryl coenzyme A (IB-CoA), a short-chain branched acyl-CoA, provides the starter unit for biosynthesis of myxalamid B. Isobutyryl coenzyme A is used as a substrate to study the specificity and kinetics of isobutyryl-coenzyme A (CoA) mutase (EC 5.4.99.13).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Helge B Bode et al.
Chembiochem : a European journal of chemical biology, 8(17), 2139-2144 (2007-10-24)
Myxalamids are potent inhibitors of the eukaryotic electron transport chain produced by different myxobacteria. Here, we describe the identification of the myxalamid biosynthesis gene cluster from Myxococcus xanthus. Additionally, new myxalamids (5-13) have been obtained by mutasynthesis from bkd mutants
Jinxia Lin et al.
Bioresource technology, 102(2), 1863-1868 (2010-10-29)
Supply of isobutanol to enhance the production of anti-tumor agent ansamitocin P-3 (AP-3) in medium containing agro-industrial residues was investigated with analysis of gene transcription, enzyme activity, and intermediate accumulation. Under the optimal addition of isobutanol, about 4-fold improvement of
Mohini S Ghatge et al.
Applied and environmental microbiology, 75(11), 3469-3476 (2009-03-24)
Phoslactomycins (PLMs) and related leustroducsins (LSNs) have been isolated from a variety of bacteria based on antifungal, anticancer, and other biological assays. Streptomyces sp. strain HK 803 produces five PLM analogs (PLM A and PLMs C to F) in which
A Ratnatilleke et al.
The Journal of biological chemistry, 274(44), 31679-31685 (1999-10-26)
Isobutyryl-CoA mutase (ICM) catalyzes the reversible, coenzyme B(12)-dependent rearrangement of isobutyryl-CoA to n-butyryl-CoA, which is similar to, but distinct from, that catalyzed by methylmalonyl-CoA mutase. ICM has been detected so far in a variety of aerobic and anaerobic bacteria, where

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