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G211180

DMT-2′O-Methyl-rG(ib)-Phosphoramidit

configured for PerkinElmer, configured for Polygen

Synonym(e):

DMT-2′-O-Me-rG(ib)-Amidit, N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-guanosin, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit]

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Größe/SKUVerfügbarkeitPreis
0.5 g
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€ 95,70
1 g
Warenkorb auf Verfügbarkeit prüfen
€ 133,00

Über diesen Artikel

Empirische Formel (Hill-System):
C45H56N7O9P
CAS-Nummer:
Molekulargewicht:
869.94
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41116105
MDL number:
Assay:
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
Form:
powder

€ 95,70


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biological source

non-animal source (no BSE/TSE risk)

Quality Segment

product line

Proligo Reagents

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

form

powder

technique(s)

oligo synthesis: suitable

impurities

≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3% residual Solvent content

color

white to off-white

λ

conforms (UV/VIS Identity)

suitability

conforms to structure for H-NMR, conforms to structure for LC-MS

compatibility

configured for PerkinElmer, configured for Polygen

nucleoside profile

base: guanosine
base protecting group: isobutyryl
2' protecting group: methyl
5' protecting group: DMT
deprotection: standard

storage temp.

-10 to -25°C

SMILES string

CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1n5cnc6C(=O)NC(NC(=O)C(C)C)=Nc56

InChI

1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1

InChI key

IRRDHRZUOZNWDJ-MLLDKZSOSA-N


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Dieser Artikel
G211140G211100G211130
description

configured for PerkinElmer, configured for Polygen

description

configured for MerMade

description

-

description

configured for ABI

assay

≥99.0% (reversed phase HPLC), ≥99% (31P-NMR)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

assay

≥99.0% (reversed phase HPLC), ≥99% (31P-NMR)

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

storage temp.

-10 to -25°C

storage temp.

-10 to -25°C

storage temp.

-10 to -25°C

storage temp.

-10 to -25°C

form

powder

form

powder

form

powder

form

powder

impurities

≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤3% residual Solvent content, ≤0.3% water content (Karl Fischer)

impurities

≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3% residual Solvent content, ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.5% single Impurity (redox titration), ≤0.3% water content (Karl Fischer)

impurities

≤0.3 wt. % water content (Karl Fischer), ≤3 wt. % residual Solvent content, ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT)

impurities

≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤3% residual Solvent content, ≤0.3% water content (Karl Fischer), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate)

product line

Proligo Reagents

product line

Proligo Reagents

product line

-

product line

Proligo Reagents


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Lagerklasse

11 - Combustible Solids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable



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