G211130

DMT-2′O-Methyl-rG(ib)-Phosphoramidit

configured for ABI

• Synonym(e): DMT-2′-O-Me-rG(ib)-Amidit, N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-guanosin, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit]
• Empirische Formel (Hill-System): C₄₅H₅₆N₇O₉P
• CAS-Nummer: 150780-67-9
• Molekulargewicht: 869.94
• NACRES: NA.51
• PubChem Substance ID: 329799864
• UNSPSC Code: 41116105
• MDL number: MFCD00792625
• Assay: ≥99% (³¹P-NMR), ≥99.0% (reversed phase HPLC)
• Biological source: non-animal source (no BSE/TSE risk)
• Form: powder
• Storage temp.: -10 to -25°C

Eigenschaften

• biological source: non-animal source (no BSE/TSE risk)
• Quality Segment: 300
• product line: Proligo Reagents
• assay: ≥99% (³¹P-NMR), ≥99.0% (reversed phase HPLC)
• form: powder
• technique(s): oligo synthesis: suitable
• impurities: ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3% residual Solvent content
• color: white to off-white
• λ: conforms (UV/VIS Identity)
• suitability: conforms to structure for H-NMR, conforms to structure for LC-MS
• compatibility: configured for ABI
• nucleoside profile: base: guanosine; base protecting group: isobutyryl; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: standard
• storage temp.: -10 to -25°C
• SMILES string: CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1n5cnc6C(=O)NC(NC(=O)C(C)C)=Nc56
• InChI: 1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
• InChI key: IRRDHRZUOZNWDJ-MLLDKZSOSA-N

Beschreibung

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable