The stability of this product when prepared in DMSO has not been determined. In general, solutions in DMSO should be prepared fresh and used promptly. Epinephrine is most stable in acidic aqueous solutions at pH 3.6, when stored tightly sealed under nitrogen or argon. Solutions prepared in basic buffers are unstable and turn red in color due to degradation. Published literature indicates solutions are stable for at least 1 month when stored at 4°C or 25°C. Commercial solutions are often assigned a shelf life of greater than 1 year.
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E4250
(−)-Epinephrin
≥99% (HPLC), powder, adrenoceptor agonist
Synonym(e):
(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)-benzylalkohol, L-Adrenalin, L-Epinephrin
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About This Item
Lineare Formel:
(HO)2C6H3CH(OH)CH2NHCH3
CAS-Nummer:
Molekulargewicht:
183.20
Beilstein:
2368277
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77
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Produktbezeichnung
(−)-Epinephrin,
Qualitätsniveau
mp (Schmelzpunkt)
215 °C (dec.) (lit.)
Lagertemp.
2-8°C
SMILES String
CNC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
InChIKey
UCTWMZQNUQWSLP-VIFPVBQESA-N
Angaben zum Gen
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)
rat ... Adra1a(29412) , Adra2a(25083) , Adrb1(24925) , Adrb2(24176) , Drd1a(24316) , Drd2(24318)
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Biochem./physiol. Wirkung
Adrenoceptor-Agonist
Leistungsmerkmale und Vorteile
This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Rekonstituierung
This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
Lagerklassenschlüssel
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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When this product is reconstituted in DMSO, at what temperature should it be stored?
1 answer-
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Hi, Is it possible to reconstitute the epinephrine solution in something less aggressive than 0.5 M HCl ? Sincerely, Alex
1 answer-
This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.
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