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C2650

Sigma-Aldrich

5-Cholenic acid-3β-ol

≥98%

Synonym(e):

3β-Hydroxy-5-cholen-24-oic acid

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About This Item

Empirische Formel (Hill-System):
C24H38O3
CAS-Nummer:
5255-17-4
Molekulargewicht:
374.56
MDL-Nummer:
MFCD00069468
UNSPSC-Code:
12352211
PubChem Substanz-ID:
24892512

Assay

≥98%

SMILES String

C[C@@H](CCC(O)=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C

InChI

1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h5,15,17-21,25H,4,6-14H2,1-3H3,(H,26,27)

InChIKey

HIAJCGFYHIANNA-UHFFFAOYSA-N

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Deoxycholsäure ≥98% (HPLC)

Sigma-Aldrich

D2510

Deoxycholsäure

Dimethylsulfoxid Hybri-Max™, sterile-filtered, BioReagent, suitable for hybridoma, ≥99.7%

Sigma-Aldrich

D2650

Dimethylsulfoxid

R Hall et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2(2), 152-156 (1988-02-01)
The regulation of bile acid synthesis was studied in rabbits after interruption of the enterohepatic circulation by choledochoureteral anastomosis. Total daily bile acid output was 772 +/- 130 (SD) mumol/24 h, of which greater than 95% was glycocholic acid. Administration
J Shoda et al.
Journal of lipid research, 30(8), 1233-1242 (1989-08-01)
3 beta-Hydroxy-(delta 5-3 beta-ol), 3 beta,12 alpha-dihydroxy-(delta 5-3 beta,12 alpha-ol), 3 beta,7 alpha-dihydroxy-(delta 5-3 beta,7 alpha-ol) and 3 beta,7 beta-dihydroxy-(delta 5-3 beta,7 beta-ol) 5-cholenoic acids were identified in patients with liver diseases by gas-liquid chromatography-mass spectrometry (GLC-MS). Of these unusual
Nariyasu Mano et al.
Journal of lipid research, 45(9), 1741-1748 (2004-06-04)
We have previously demonstrated that the rat brain contains three unconjugated bile acids, and chenodeoxycholic acid (CDCA) is the most abundantly present in a tight protein binding form. The ratio of CDCA to the other acids in rat brain tissue
J Zhang et al.
The Biochemical journal, 322 ( Pt 1), 175-184 (1997-02-15)
The metabolism of 27-, 25- and 24-hydroxycholesterol in cultures of rat astrocytes, Schwann cells and neurons was studied. 27- and 25-Hydroxycholesterol, but not 24-hydroxycholesterol, underwent 7 alpha-hydroxylation with subsequent oxidation to 7 alpha-hydroxy-3-oxo-delta 4 steroids in all three cell types.
S K Krisans et al.
Journal of lipid research, 26(11), 1324-1332 (1985-11-01)
Rat liver peroxisomes have been found to oxidize 26-hydroxycholesterol, the product of cholesterol C-26 hydroxylation to 3 beta-hydroxy-5-cholenoic acid. Peroxisomes were purified by differential and equilibrium density centrifugation in a steep linear metrizamide gradient to greater than 95% purity. Purity
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