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Merck

B7929

Sigma-Aldrich

Anti-Bim antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-BOD

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 23 kDa

Speziesreaktivität

human, rat, mouse

Methode(n)

immunohistochemistry: 20 μg/mL using human skin cancer cells
microarray: suitable
western blot: 1 μg/mL using A549 or K562 whole cell lysates

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

Immunogen

synthetic peptide corresponding to amino acids 22-40 of human Bim (BOD). This sequence is identical in mouse and contains only one amino acid substitution in rat.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Nina Stojcheva et al.
Oncotarget, 7(11), 12937-12950 (2016-02-18)
Glioblastoma is the most aggressive brain tumor in adults with a median survival below 12 months in population-based studies. The main reason for tumor recurrence and progression is constitutive or acquired resistance to the standard of care of surgical resection
P Geserick et al.
Cell death & disease, 5, e1412-e1412 (2014-09-12)
Tumour progression and therapy resistance in squamous cell carcinoma of the skin (SCC) is strongly associated with resistance to intrinsic mitochondrial apoptosis. We thus investigated the role of various anti-apoptotic Bcl-2 proteins for apoptosis protection in SCC using the BH3
Violeta Gómez-Vicente et al.
The European journal of neuroscience, 24(4), 981-990 (2006-08-26)
Apoptosis of photoreceptor cells in the early postnatal period is a normal feature of mammalian retinal development. The role of mitochondria and caspases in the process has been well established; however, the identification of key apoptotic mediators still remains elusive.
Laura Elisa Buitrago-Molina et al.
Cellular and molecular gastroenterology and hepatology, 11(5), 1387-1404 (2021-01-24)
A coordinated stress and regenerative response is important after hepatocyte damage. Here, we investigate the phenotypes that result from genetic abrogation of individual components of the checkpoint kinase 2/transformation-related protein 53 (p53)/cyclin-dependent kinase inhibitor 1A (p21) pathway in a murine
L O'Connor et al.
The EMBO journal, 17(2), 384-395 (1998-02-28)
Certain members of the Bcl-2 family inhibit apoptosis while others facilitate this physiological process of cell death. An expression screen for proteins that bind to Bcl-2 yielded a small novel protein, denoted Bim, whose only similarity to any known protein

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