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Merck

58756

Sigma-Aldrich

1-(5-Isochinolinylsulfonyl)-3-methyl-piperazin

≥98.0% (HPLC)

Synonym(e):

1-(5-Isochinolinsulfonyl)-3-methylpiperazin, Iso-H-7

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5 MG
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€ 89,30

About This Item

Empirische Formel (Hill-System):
C14H17N3O2S
CAS-Nummer:
Molekulargewicht:
291.37
Beilstein:
5445506
MDL-Nummer:
UNSPSC-Code:
12352202
PubChem Substanz-ID:
NACRES:
NA.77

€ 89,30


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Qualitätsniveau

Assay

≥98.0% (HPLC)

Form

powder

Lagertemp.

2-8°C

SMILES String

CC1CN(CCN1)S(=O)(=O)c2cccc3cnccc23

InChI

1S/C14H17N3O2S/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14/h2-6,9,11,16H,7-8,10H2,1H3

InChIKey

QGSCXAWTTISKLF-UHFFFAOYSA-N

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Biochem./physiol. Wirkung

weniger wirksames Inhibitor von Phosphokinase C im Vergleich zu H-7

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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J Kreuzer et al.
Journal of molecular medicine (Berlin, Germany), 74(3), 161-165 (1996-03-01)
The accumulation of blood monocytes at sites of predilection of the vessel wall is an early cellular event of atherogenesis. Proteins of the vessel wall may facilitate monocyte adhesion and thus promote their recruitment. It has been shown that the
V Ladeda et al.
Experimental cell research, 242(2), 515-527 (1998-07-31)
The cell surface glycoprotein CD44 is proposed as a main participant in cell adhesion and migration. We studied the function, expression, and distribution of CD44 in the invasive and metastatic F3II murine carcinoma cell line during adhesion, spreading, migration, and
T Miyashita et al.
Receptors & channels, 7(2), 77-91 (2000-08-22)
We previously reported that the metabotropic glutamate receptor R1alpha (mGluR1alpha) can be activated not only by applying glutamate but also by raising extracellular Ca2+ (Ca2+o) concentration, and that the constant stimulation by Ca2+o causes morphological change of transfected Chinese Hamster
K Fujisawa et al.
Placenta, 21(4), 354-360 (2000-06-02)
To clarify the biological and pathological features of choriocarcinoma, we evaluated the in vitro production of cytokines by a choriocarcinoma cell line, BeWo. We measured the concentration of interleukin (IL)-6 and IL-8 in the culture media of BeWo cells after
Mei-Hua Li et al.
Zhonghua er bi yan hou ke za zhi, 39(6), 353-355 (2004-10-08)
To study the influence of the inhibitor of protein kinase C (PKC), Iso-H7 [1-(5-lsoquinolinyl-sulfony)-3-methylpiperazine dihydrochloride] on eosinophil apoptosis in nasal polyp tissues. Nasal polyp tissues were cultured and divided into two groups, test group (with Iso-H7 in different concentration) and

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