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PHR1394

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Fluoxetin-Hydrochlorid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Fluoxetin -hydrochlorid, (±)-N-Methyl-γ-[4-(trifluormethyl)-phenoxy]-benzolpropanamin -hydrochlorid, LY-110,140 -hydrochlorid, Prozac®

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About This Item

Empirische Formel (Hill-System):
C17H18F3NO · HCl
CAS-Nummer:
Molekulargewicht:
345.79
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to BP 797
traceable to Ph. Eur. F0253000
traceable to USP 1279804

API-Familie

fluoxetine

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

InChIKey

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Angaben zum Gen

human ... SLC6A4(6532)

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Fluoxetine Hydrochloride is a selective serotonin-reuptake inhibitor used as an antidepressant. It is also utilized for the treatment of obsessive-compulsive disorders.

Anwendung

Fluoxetine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Selektiver Serotonin-Wiederaufnahmehemmer; Antidepressivum.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3045 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Rechtliche Hinweise

Verkauf lizenziert von Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Simultaneous RP-HPLC and HPTLC Estimation of Fluoxetine Hydrochloride and Olanzapine in Tablet Dosage Forms
Patel S and Patel NJ
Indian Journal of Pharmaceutical Sciences, 71(4), 477-477 (2009)
Quality assessment of internet pharmaceutical products using traditional and non-traditional analytical techniques
Westenberger BJ, et al.
International Journal of Pharmaceutics, 306(1), 56-70 (2005)
Determination of fluoxetine hydrochloride enantiomeric excess using high-performance liquid chromatography with chiral stationary phases
Olsen BA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 17(4), 623-630 (1998)
Francisco Javier Maza et al.
The Journal of experimental biology, 226(8) (2023-03-21)
The interactions between memory processes and emotions are complex. Our previous investigations in the crab Neohelice led to an adaptation of the affective extension of sometimes opponent processes (AESOP) model. The model proposes that emotions generate separate emotive memory traces
Jie Cheng et al.
Biochemical pharmacology, 168, 91-99 (2019-06-30)
Puerarin, a well-studied isoflavone isolated from Pueraria lobata, produces an antidepressant-like effect. Fibroblast growth factor-2 (FGF-2) is essentially required in the central nervous system as it acts as both a neurotrophic or anti-inflammatory regulator for the proliferation, differentiation and apoptosis

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