This product is intended for use as an analytical standard and has not been tested for suitability in cell culture applications. As per available literature, it does appear to be cell permeable, While it is tested against the USP and EP standards, it is not sterile or endotoxin tested.
See the link below for a publication that may be helpful.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181147/
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PHR1333
(−)-Epigallokatechingallat
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(e):
(−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallat, (−)-cis-3,3′,4′,5,5′,7-Hexahydroxy-Flavan-3-Gallat, EGCG
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€ 108,00
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About This Item
Empirische Formel (Hill-System):
C22H18O11
CAS-Nummer:
Molekulargewicht:
458.37
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24
Empfohlene Produkte
Qualität
certified reference material
pharmaceutical secondary standard
Qualitätsniveau
Agentur
traceable to USP 1236700
API-Familie
catechins
Analysenzertifikat (CofA)
current certificate can be downloaded
Methode(n)
HPLC: suitable
gas chromatography (GC): suitable
Anwendung(en)
pharmaceutical (small molecule)
Format
neat
Lagertemp.
2-8°C
SMILES String
Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4
InChI
1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
InChIKey
WMBWREPUVVBILR-WIYYLYMNSA-N
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Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Epigallocatechin gallate is a potent polyphenolic flavonoid which is found as a component of tea. It exhibits antioxidant, antimutagenic, antitumor and anti-inflammatory properties, thereby contributing to the health-beneficial actions. It finds potential use as a drug candidate in the pharmaceutical, cosmetic, and nutritional fields.[1]
Epigallocatechin gallate is a potent polyphenolic flavonoid which is found as a component of tea. It exhibits antioxidant, antimutagenic, antitumor and anti-inflammatory properties, thereby contributing to the health-beneficial actions. It finds potential use as a drug candidate in the pharmaceutical, cosmetic, and nutritional fields.[1]
Anwendung
Epigallocatechin gallate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.[2][1][3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Hinweis zur Analyse
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Sonstige Hinweise
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Fußnote
To see an example of a Certificate of Analysis for this material enter LRAC4432 in the slot below. This is an example certificate only and may not be the lot that you receive.
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Produkt-Nr.
Beschreibung
Preisangaben
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Hier finden Sie alle aktuellen Versionen:
Analysenzertifikate (COA)
Lot/Batch Number
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Jana Adamcakova et al.
International journal of molecular sciences, 24(3) (2023-02-12)
Inhalation of silica particles causes inflammatory changes leading to fibrotizing silicosis. Considering a lack of effective therapy, and a growing information on the wide actions of green tea polyphenols, particularly epigallocatechin-3-gallate (EGCG), the aim of this study was to evaluate
Wajdy Al-Awaida et al.
Molecules (Basel, Switzerland), 28(22) (2023-11-25)
Exposure to water-pipe smoking, whether flavored or unflavored, has been shown to instigate inflammation and oxidative stress in BALB/c mice. This consequently results in alterations in the expression of inflammatory markers and antioxidant genes. This study aimed to scrutinize the
Enhanced uptake and transport of (+)-catechin and (-)-epigallocatechin gallate in niosomal formulation by human intestinal Caco-2 cells
Song Q, et al.
International journal of nanomedicine, 9(1), 2157-2157 (2014)
Jung-Ah Cho et al.
Scientific reports, 12(1), 18669-18669 (2022-11-06)
Biofilm formation is one of the leading causes of complications after surgery in clinical settings. In this study, we profiled the biofilm-forming ability of various periprosthetic infection-associated pathogens on medically relevant surfaces, polystyrene (PS) and titanium (Ti). We also explored
Euphorbia denticulata Lam.: A promising source of phyto-pharmaceuticals for the development of novel functional formulations
Zengin G, et al.
Biomedicine and Pharmacotherapy, 87(1), 27-36 (2017)
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