If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
E1753
(−)-Epicatechin
≥90% (HPLC)
Synonym(e):
(−)-cis-3,3′,4′,5,7-Pentahydroxyflavan, (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
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€ 589,00
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InChI key
PFTAWBLQPZVEMU-UKRRQHHQSA-N
InChI
1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1
SMILES string
O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3
assay
≥90% (HPLC)
form
powder
mp
240 °C (dec.) (lit.)
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
Quality Level
Gene Information
human ... BACE1(23621), CYP1A2(1544)
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1 of 4
Dieser Artikel | |||
|---|---|---|---|
| form powder | form - | form - | form - |
| assay ≥90% (HPLC) | assay ≥98% (HPLC) | assay - | assay ≥97.0% (HPLC) |
| application(s) metabolomics | application(s) metabolomics | application(s) food and beverages | application(s) food and beverages |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level 100 |
| mp 240 °C (dec.) (lit.) | mp 240 °C (dec.) (lit.) | mp 240 °C (dec.) (lit.) | mp 240 °C (dec.) (lit.) |
| Gene Information human ... BACE1(23621), CYP1A2(1544) | Gene Information human ... BACE1(23621), CYP1A2(1544) | Gene Information - | Gene Information - |
General description
Application
- als Antioxidans zur Herunterregulierung der Nikotinamid-Adenin-Dinukleotid-Phosphat-Wasserstoff-Oxidase (NADPH-Oxidase) und zur Verbesserung der Insulinsensitivität in In-vivo-Studien (mit viel Fett gefütterte Mäuse) und In-vitro-Studien (HepG2-Zellen)[2]
- zur Untersuchung seiner Wirkung auf den Blutdruck, die Aktivität der Stickstoffmonoxid-Synthase (NOS) und des angstähnlichen Verhaltens an Modellen der borderline-hypertensiven Ratte (BHR)[3]
- zur Untersuchung seiner Wirkung auf das neuronale Überleben im Hippocampus von Ratten mittleren Alters bei Schwimmtraining unter oxidativem Stress[4]
- zur Untersuchung seiner antioxidativen Aktivität in dunkler Schokolade[5]
- als charakteristische Verbindung in der Polyphenolanalyse[6]
Biochem/physiol Actions
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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