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Merck

909564

Sigma-Aldrich

4-Azido-L-phenylalanine

≥98%

Synonym(e):

3-(p-Azidophenyl)-L-alanine hydrochloride, 4-Azidophenylalanine hydrochloride, 4-N3-L-Phenylalanine, p-Azido-L-phenylalanine hydrochloride, p-Azido-Phe*HCl, p-Azidophenylalanine hydrochloride, H-4-Azido-Phe*HCl, H-L-4-Azido-Phe-OH, H-L-Phe(4-N3)-OH, H-Phe(4-N3)*HCl, Phe(pN3)*HCl

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About This Item

Empirische Formel (Hill-System):
C9H10N4O2
CAS-Nummer:
Molekulargewicht:
206.20
MDL-Nummer:
UNSPSC-Code:
12352005

Assay

≥98%

Form

powder

Eignung der Reaktion

reaction type: click chemistry
reaction type: solution phase peptide synthesis

Verfügbarkeit

available only in USA

Lagertemp.

−20°C

InChI

1S/C9H10N4O2/c10-8(9(14)15)5-6-1-3-7(4-2-6)12-13-11/h1-4,8H,5,10H2,(H,14,15)/t8-/m0/s1

InChIKey

NEMHIKRLROONTL-QMMMGPOBSA-N

Anwendung

The in-vivo incorporation of clickable unnatural amino acids such as 4-Azido-L-phenylalanine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.

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Piktogramme

Flame

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Self-react. C

Lagerklassenschlüssel

5.2 - Organic peroxides and self-reacting hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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