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Merck

70079

Supelco

Myristinsäure

analytical standard

Synonym(e):

1-Tridecancarbonsäure, C14:0, NSC 5028, Tetradecansäure

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About This Item

Lineare Formel:
CH3(CH2)12COOH
CAS-Nummer:
Molekulargewicht:
228.37
Beilstein:
508624
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Assay

≥99.5% (GC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

bp

250 °C/100 mmHg (lit.)

mp (Schmelzpunkt)

52-54 °C (lit.)
53-56 °C

Anwendung(en)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Format

neat

SMILES String

CCCCCCCCCCCCCC(O)=O

InChI

1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)

InChIKey

TUNFSRHWOTWDNC-UHFFFAOYSA-N

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Allgemeine Beschreibung

Myristic acid is an important bioactive component of Suanzaoren seed, which is one of the most commonly used Chinese medicine with therapeutic properties such as hypotensive, antihypoxia, hypnotic-sedative, antihyperlipidemia, and hypothermic effects.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Anwendung

Myristic acid may be used as an analytical reference standard for the quantification of the anayte in Ziziphus jujuba using high performance liquid chromatography with evaporative light scattering detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sonstige Hinweise

Bindung an Serum Albumin

Lagerklassenschlüssel

11 - Combustible Solids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Analysenzertifikate (COA)

Lot/Batch Number

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A O Pedersen et al.
The Journal of biological chemistry, 263(21), 10236-10239 (1988-07-25)
Dialysis rate determinations of several fatty acids in the absence of albumin revealed that the myristate anion, like that of laurate, in aqueous solution, pH 7.5, is present as a monomer anion when the concentration is below 25 microM. Palmitate
Simultaneous determination of saponins and fatty acids in Ziziphus jujuba (Suanzaoren) by high performance liquid chromatography-evaporative light scattering detection and pressurized liquid extraction
Zhao.J, et al.
Journal of Chromatography A, 1108(2), 188-194 (2006)
Dalit Shental-Bechor et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(44), 17839-17844 (2012-08-01)
We present an integrated experimental and computational study of the molecular mechanisms by which myristoylation affects protein folding and function, which has been little characterized to date. Myristoylation, the covalent linkage of a hydrophobic C14 fatty acyl chain to the
Sarah Brice Russo et al.
The Journal of clinical investigation, 122(11), 3919-3930 (2012-10-02)
Diabetic cardiomyopathy (DbCM), which consists of cardiac hypertrophy and failure in the absence of traditional risk factors, is a major contributor to increased heart failure risk in type 2 diabetes patients. In rodent models of DbCM, cardiac hypertrophy and dysfunction
Nikolay Burnaevskiy et al.
Nature, 496(7443), 106-109 (2013-03-29)
Protein N-myristoylation is a 14-carbon fatty-acid modification that is conserved across eukaryotic species and occurs on nearly 1% of the cellular proteome. The ability of the myristoyl group to facilitate dynamic protein-protein and protein-membrane interactions (known as the myristoyl switch)

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