41144

β-Alanin

analytical standard

• Synonym(e): β-Ala, 3-Aminopropionsäure
• Lineare Formel: NH₂CH₂CH₂COOH
• CAS-Nummer: 107-95-9
• Molekulargewicht: 89.09
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329756061
• EC Number: 203-536-5
• Beilstein/REAXYS Number: 906793
• MDL number: MFCD00008200

Eigenschaften

• grade: analytical standard
• Quality Level: 100
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• analyte chemical class(es): amino acids, peptides, proteins
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• impurities: ≤0.3% water
• color: white to off-white
• mp: 202 °C (dec.) (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• format: neat
• SMILES string: NCCC(O)=O
• InChI: 1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
• InChI key: UCMIRNVEIXFBKS-UHFFFAOYSA-N

Beschreibung

General description

β-Alanine is a rate-limiting precursor of carnosine, a cytoplasmic dipeptide which is present in human skeletal muscles in high concentrations.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

β-Alanine may be used as a reference standard for the determination of β-alanine in:

• Potato tubers by gas chromatography-mass spectrometry (GC-MS).
• Human plasma, urine, and cerebrospinal fluid samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
• Striatal microdialysis samples by high performance liquid chromatography-fluorescence detection (HPLC-FLD) with ortho-phthalaldehyde-mercaptoethanol derivatization.
• Fermented soybean paste, Cheonggukjang, by GC-MS operating in selected-ion monitoring (SIM) mode and principal component analysis (PCA).

Biochem/physiol Actions

Endogene β-Aminosäure, bei der es sich um einen nicht-selektiven Agonisten an Glycin-Rezeptoren und einen Liganden für den G-Protein-gekoppelten Orphan-Rezeptor, TGR7 (MrgD), handelt. β-Alanin ist eine Komponente von Pantothensäure.

Diese endogene β-Aminosäure ist ein unselektiver Agonist von Glycin-Rezeptoren und ein Ligand des G-Protein-gekoppelten Orphan Rezeptors TGR7 (MrgD). Der β-Alaninfluss spielt eine zellschützende Rolle indem er die osmotische Stabilität von Meeresorganismen, preimplantation-Mausembryos und Säugerzellen unter hypoxischem Stress stabilisiert.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable