37022

(−)-Scopolamin -hydrochlorid

analytical standard

• Synonym(e): Hyoscin -hydrochlorid, Scopin-tropat
• Empirische Formel (Hill-System): C₁₇H₂₁NO₄ · HCl
• CAS-Nummer: 55-16-3
• Molekulargewicht: 339.81
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329755587
• EC Number: 200-225-6
• Beilstein/REAXYS Number: 4168778
• MDL number: MFCD00058096

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• storage temp.: −20°C
• SMILES string: Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
• InChI key: KXPXJGYSEPEXMF-MOUKNHLCSA-N
• Gene Information: human ... CHRM1(1128)

Beschreibung

General description

(−)-Scopolamine hydrochloride belongs to the class of naturally occurring tropane alkaloids of medicinal interest, found in several members of the Solanaceae family, commonly Atropa belladonna and representatives of the genera Datura and Duboisia.

For the analysis of the phytotoxins.

Application

(−)-Scopolamine hydrochloride may be used as a precursor for the preparation of scopolamine, employed as an analytical standard for the quantification of the scopolamine in the floral nectar and plant organs of Datura species using various chromatographic techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Kompetitiver, nichtselektiver muskarinischer Acetylcholin-Antagonist.

Kompetitiver, nichtselektiver muskarinischer Acetylcholin-Antagonist. Scopolamin-induzierte Amnesie bei Labortieren ist ein häufig verwendetes Modell von Gedächtnis-Defizit.

Preparation Note

Dried down, Konzentratio von (S)-(-)-Scopolamine (freie Base) nach Rücklösung 100 μg/mL

Analysis Note

purity : ≥96.0% (HPLC)

Sicherheitshinweise

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H300 + H310 + H330,H317,H318
• pcodes: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable