HCYTMAG-60K-PX29

MILLIPLEX^® Human Cytokine/Chemokine Magnetic Bead Panel - Premixed 29 Plex - Immunology Multiplex Assay

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

• Synonym(e): Human cytokine multiplex kit, Luminex^® human cytokine immunoassay, Millipore human cytokine panel
• UNSPSC-Code: 12161503
• eCl@ss: 32161000

Eigenschaften

• Speziesreaktivität: human
• Hersteller/Markenname: Milliplex^®
• assay range: accuracy: 87-107%; standard curve range: 3.2-10,000 pg/mL
• Methode(n): multiplexing: suitable
• Kompatibilität: configured for Premixed
• Nachweisverfahren: fluorometric (Luminex xMAP)
• Versandbedingung: wet ice

Beschreibung

Allgemeine Beschreibung

“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. Cytokines differ from hormones in that they act on a wider spectrum of target cells. Also, unlike hormones, they are not produced by specialized cells which are organized in specialized glands. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer.

The MILLIPLEX^® Human Cytokine / Chemokine Panel 1 enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cytokines/Chemokines

Spezifität

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Anwendung

• Analytes: EGF, G-CSF, GM-CSF, IFN-α2, IFN-γ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IP-10, MCP-1, MIP-1α, MIP-1β, TNF-α, TNF-β, VEGF, Eotaxin/CCL11
• Recommended Sample type: Serum, plasma, or tissue/cell lysate and culture supernatant samples
• Recommended Sample dilution: Neat plasma or serum. Tissue culture supernatant may require a dilution with an appropriate control medium prior to assay.
• Assay Run Time: Overnight or two-hour primary incubation. For best results, an overnight incubation is recommended
• Research Category: Inflammation & Immunology
• Research Subcategory: Obesity, Metabolic Disorders, Inflammation & Autoimmune Mechanisms

Verpackung

96 well plate

Lagerung und Haltbarkeit

Recommended storage for kit components is 2 - 8°C.

Sonstige Hinweise

Note: RANTES, PDGF-AA and PDGF-AB/AA cannot be plexed with other analytes for serum/plasma.

Sensitivity: Refer to kit protocol for sensitivities for individual cytokines/chemokines.

Rechtliche Hinweise

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H302 + H332,H311,H317,H318,H373,H411
• P-Sätze: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Zielorgane: Respiratory Tract
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects