Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defense against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
Spezifität
This isotype control shows negligible cross-reactivity with human cell surface antigens on tissue sections or in cellular preparations. It therefore enables the estimation of non-specific binding of mouse monoclonals to cell surface antigens.
Anwendung
Research Category Sekundär- & Kontrollantikörper
Research Sub Category Epitop-Tags
Mouse IgG1 Negative Control Monoclonal Antibody validated for use in Flow Cytometry.
Qualität
Evaluated by Flow Cytometry in HeLa cells. Flow Cytometry Analysis: 2 µg of this antibody was used as a Mouse IgG1 Negative Control in staining of HeLa cells.
Verlinkung
Replaces: CBL600
Physikalische Form
Protein G
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Lagerung und Haltbarkeit
Stable for 1 year at 2-8°C from date of receipt.
Hinweis zur Analyse
Control HeLa cells
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Minimum order quantity required to qualify. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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