8.52243

Fmoc-D-Dpr(ivDde)-OH

Novabiochem^®

• Synonym(e): N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-D-diaminopropionic acid
• Empirische Formel (Hill-System): C₃₁H₃₆N₂O₆
• CAS-Nummer: 1228900-15-9
• Molekulargewicht: 532.63
• UNSPSC-Code: 12352209
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Produktlinie: Novabiochem^®
• Assay: ≥90.0% (acidimetric); ≥95.0% (HPLC); ≥98% (TLC)
• Form: powder
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis
• Hersteller/Markenname: Novabiochem^®
• Anwendung(en): peptide synthesis; peptide synthesis
• Funktionelle Gruppe: amine
• Lagertemp.: 15-25°C

Beschreibung

Allgemeine Beschreibung

This orthogonally-protected derivative is based on the hindered Dde variant ivDde. It has very similar chemical properties to Fmoc-Lys(Dde)-OH, except that the side-chain ivDde group is considerably more stable to piperidine than Dde, and is less prone to migrate from protected to unprotected lysine side-chains. When removing ivDde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Verlinkung

Replaces: 04-13-1074

Hinweis zur Analyse

Farbe (visuell): weiß bis schwach gelb bis beige
Aussehen der Substanz (visuell): Pulver
Identität (IR): entspricht
Enantiomerenreinheit: ≥ 99.0 % (a/a)
Reinheit (DC(157A)): ≥ 98 %
Reinheit (DC(CMA2)): ≥ 98 %
Gehalt (HPLC, Fl.%): ≥ 95.0 % (a/a)
Wasser (K. F.): ≤ 1.0 %
Gehalt (acidimetrisch): ≥ 90.0 %
DC-Bedingungen gemäß den Angaben unseres Hauptkataloges

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable