5.04467

L-CCG-I

• Synonym(e): L-CCG-I
• Empirische Formel (Hill-System): C₆H₉NO₄
• CAS-Nummer: 117857-93-9
• Molekulargewicht: 159.14
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥97% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white
• Löslichkeit: aqueous base: soluble
• Lagertemp.: 2-8°C
• InChI: 1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3-,4-/m0/s1
• InChIKey: GZOVEPYOCJWRFC-HZLVTQRSSA-N

Beschreibung

Allgemeine Beschreibung

A potent agonist for group II metabotropic glutamate receptors (EC₅₀ = 0.49 µM and 0.44 µM for mGlu₂ and mGlu₃, respectively). Higher level of activity than glutamate or (±)-trans-ACPD. Widely used in studies related to neurotransmissions mediated via group II mGlu receptors.

Biochem./physiol. Wirkung

Primary Target
mGlu₂ & mGlu₃

Warnhinweis

Toxicity: Standard Handling (A)

Sonstige Hinweise

Shinozaki, H., et al. 1989. Br. J. Pharmacol.98, 1213.
Hayashi, Y., et al. 1992. Br. J. Pharmacol.107, 539.
Nakanishi,S. 1992. Science.258, 597.
Watkins, J., et al. 1994. Trends Pharmacol Sci.15, 333.
Schoepp, D.D., et al. 1999. Neuropharmacology.38, 1431.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable