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Merck
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Dokumente

07-402

Sigma-Aldrich

Anti-p70 S6 Kinase Antibody

Upstate®, from rabbit

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human, mouse, rat

Verpackung

antibody small pack of 25 μg

Hersteller/Markenname

Upstate®

Methode(n)

immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_003161

UniProt-Hinterlegungsnummer

P23443

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... RPS6KB1(6198)

Spezifität

p70 S6 kinase

Immunogen

peptide corresponding to amino acids 26-43 of rat p70 S6 Kinase, with an N-terminal cysteine

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
PI3K-, Akt-, & mTOR-Signalübertragung
Anti-p70 S6 Kinase Antibody is an antibody against p70 S6 Kinase for use in IP & WB.

Qualität

routinely evaluated by immunoblot in RIPA lysates from HEK293, PC-12,and A431 cells

Zielbeschreibung

64 kDa

Verlinkung

Replaces: 04-391

Physikalische Form

Protein A purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells.
Ballou, L M, et al.
The Journal of Biological Chemistry, 263, 1188-1194 (1988)
A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation.
Reinhard, C, et al.
Proceedings of the National Academy of Sciences of the USA, 89, 4052-4056 (1992)
Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells.
Baxter, R M, et al.
European Journal of Biochemistry, 234, 84-91 (1995)
Jason P Chua et al.
Human molecular genetics, 23(5), 1376-1386 (2013-10-24)
Spinobulbar muscular atrophy (SBMA) is an inherited neuromuscular disorder caused by the expansion of a CAG repeat encoding a polyglutamine tract in exon 1 of the androgen receptor (AR) gene. SBMA demonstrates androgen-dependent toxicity due to unfolding and aggregation of
Zhiguang Xiao et al.
Oncotarget, 5(24), 12877-12890 (2014-11-07)
The presence of cancer stem cells (CSCs) is linked to preexisting or acquired drug resistance and tumor relapse. Therefore, targeting both differentiated tumor cells and CSCs was suggested as an effective approach for non-small cell lung cancer (NSCLC) treatment. After

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