RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
Synonyms:
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Species:
Human RPS6KB1 (6198), Mouse Rps6kb1 (72508), Rat Rps6kb1 (83840), cow RPS6KB1 (404181), sheep RPS6KB1 (101107371), chicken RPS6KB1 (417637), Domestic Rabbit RPS6KB1 (100009260), domestic cat RPS6KB1 (101092561), Horse RPS6KB1 (100057481), dog RPS6KB1 (480580) ...More
UniProtKB ID:
Gene ID:
- Human(6198) Summary: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
- Mouse(72508) ribosomal protein S6 kinase, polypeptide 1
- Rat(83840) ribosomal protein S6 kinase, polypeptide 1
- cow(404181) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- sheep(101107371) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- chicken(417637) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- Domestic Rabbit(100009260) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- domestic cat(101092561) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- Horse(100057481) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- dog(480580) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- domestic guinea pig(100727216) ribosomal protein S6 kinase, 70kDa, polypeptide 1
- naked mole-rat(101724077) ribosomal protein S6 kinase, 70kDa, polypeptide 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-p-RPS6KB1 (Thr389) Antibody, clone 1K19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, goat, mouse, rabbit, rat
Application
ELISA
inhibition assay
western blot
inhibition assay
western blot
Monoclonal Anti-RPS6KB1, (C-terminal) antibody produced in mouse, clone 1E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-phospho-p70 S6 Kinase (pThr421) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-p70 S6 Kinase (pSer418) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Phospho-p70 S6 Kinase 1-Thr421 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
p70S6K, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
p70S6K active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
p70 S6 Kinase Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase, for use in Kinase Assays.,
Species
human
esiRNA
Product Number
Description
Species