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Anti-mGluR2/3 Antibody

Upstate®, from rabbit

Synonym(e):

Anti-GLUR2, Anti-MGLUR2, Anti-mGlu2

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200 μG
€ 626,00

€ 626,00


Voraussichtliches Versanddatum15. April 2025


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200 μG
€ 626,00

About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

€ 626,00


Voraussichtliches Versanddatum15. April 2025


Bulk-Bestellung anfordern

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human, rat

Hersteller/Markenname

Upstate®

Methode(n)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

rat ... Grm2(24415)

Verwandte Kategorien

Spezifität

mGluR2 and mGluR3

Immunogen

peptide (KQFVPTVCNGREVVDSTTSSL) corresponding to amino acids 853-872 of human metabotropic glutamate receptor 2

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurotransmitter & Rezeptoren

Neurodegenerative Krankheiten
Anti-mGluR2/3 Antibody is an antibody against mGluR2/3 for use in IH, IP & WB.

Qualität

routinely evaluated by immunoblot on rat brain microsomal preparation

Zielbeschreibung

100-110kDa

Physikalische Form

Protein A chromatography
0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol
Format: Purified

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


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M Behnam Ghasemzadeh et al.
Pharmacology, biochemistry, and behavior, 92(3), 383-392 (2009-01-13)
Glutamatergic neurotransmission plays an important role in the behavioral and molecular plasticity observed in cocaine mediated locomotor sensitization. Recent studies show that glutamatergic signaling is regulated by receptor trafficking, synaptic localization, and association with scaffolding proteins. The trafficking of the
Patrick A Randall et al.
Alcoholism, clinical and experimental research, 43(1), 48-60 (2018-11-08)
Growing evidence suggests that neuroimmune signaling via Toll-like receptors (TLRs) alters brain circuitry related to alcohol use disorders. Both ethanol (EtOH) exposure and the TLR3 agonist, poly(I:C), increase brain TLR3 expression in neurons and glia. Furthermore, previous studies have shown
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.
Shigemoto, R, et al.
The Journal of Neuroscience, 17, 7503-7522 (1997)
Yoshiaki Miyamoto et al.
The international journal of neuropsychopharmacology, 20(12), 1027-1035 (2017-10-12)
Several clinical studies have suggested that N-acetylaspartate and N-acetylaspartylglutamate levels in the human brain are associated with various psychiatric disorders, including major depressive disorder. We have previously identified Shati/Nat8l, an N-acetyltransferase, in the brain using an animal model of psychosis.
L Emile et al.
Neuropharmacology, 35(5), 523-530 (1996-05-01)
Glutamic acid is the major excitatory amino acid of the central nervous system which interacts with two receptor families, the ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors (mGluRs) are coupled to G proteins and can be divided into

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