F-903

Fluphenazine dihydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₂₂H₂₆N₃OSF₃ · H₂Cl₂
• CAS-Nummer: 146-56-5
• Molekulargewicht: 510.44
• MDL-Nummer: MFCD00055212
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329799780
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Qualitätsniveau: 300
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• Konzentration: 1.0 mg/mL in methanol (as free base)
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): clinical testing
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: FC(F)(F)c1cc2c(cc1)Sc3c(cccc3)N2CCC[N+H]4CC[N+H](CC4)CCO.[Cl-].[Cl-]
• InChI: 1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
• InChIKey: MBHNWCYEGXQEIT-UHFFFAOYSA-N
• Angaben zum Gen: human ... DRD2(1813)

Beschreibung

Allgemeine Beschreibung

Fluphenazine, sold under the trade name Prolixin^®, is a typical antipsychotic prescribed for treatment of schizophrenia, mania, bipolar disorder and dementia. This certified solution standard is suitable for fluphenazine testing methods by GC/MS or LC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Anwendung

• Monitoring Fluphenazine Metabolites in Schizophrenia: A study developed a radioimmunoassay for the 7-hydroxy metabolite of fluphenazine, applied to monitor plasma levels in patients treated long-term with oral and depot fluphenazine. This research enhances understanding of fluphenazine′s pharmacokinetics and aids in optimizing treatment regimens for schizophrenia, contributing to personalized medicine approaches (Aravagiri et al., 1994).


• Neuroleptics in Clinical Practice: A review discusses the development and application of assays for neuroleptics, including fluphenazine, providing clinical perspectives on their use. This research is vital for enhancing therapeutic strategies and understanding the pharmacological profiles of antipsychotic drugs, which are crucial in treating severe mental disorders (Midha et al., 1993).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Prolixin is a registered trademark of E.R. Squibb & Sons, LLC

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes,Central nervous system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup