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900125E

Avanti

17(S)-HDHA

Avanti Research - A Croda Brand 900125E, ethanol solution

Synonym(e):

17(S)-hydroxy Docosahexaenoic acid

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100 μG
€ 238,00
500 μG
€ 790,00

€ 238,00


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100 μG
€ 238,00
500 μG
€ 790,00

About This Item

Empirische Formel (Hill-System):
C22H32O3
CAS-Nummer:
Molekulargewicht:
344.49
MDL-Nummer:
UNSPSC-Code:
12352211
NACRES:
NA.25

€ 238,00


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Form

ethanol solution

Verpackung

pkg of 1 × 1 mL (900125E-100ug)
pkg of 1 × 1 mL (900125E-500ug)

Hersteller/Markenname

Avanti Research - A Croda Brand 900125E

Konzentration

0.1 mg/mL (900125E-100ug)
0.5 mg/mL (900125E-500ug)

Lipid-Typ

neutral lipids
neutral glycerides

Versandbedingung

dry ice

Lagertemp.

−70°C

SMILES String

CC/C=C\C[C@H](O)/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O

InChI

1S/C22H32O3/c1-2-3-15-18-21(23)19-16-13-11-9-7-5-4-6-8-10-12-14-17-20-22(24)25/h3,5-8,11-16,19,21,23H,2,4,9-10,17-18,20H2,1H3,(H,24,25)/b7-5-,8-6-,13-11-,14-12-,15-3-,19-16+/t21-/m0/s1

InChIKey

SWTYBBUBEPPYCX-YTQNUIGOSA-N

Allgemeine Beschreibung

Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid (PUFA) with 22 carbons and six double bonds. The first double bond occurring at position three from the methyl terminus (22:6 n-3).[1] DHA is a component of phospholipid membranes and the myelin sheath. It is the most abundant PUFA found in the brain and localized predominantly to the gray matter.[2]

Biochem./physiol. Wirkung

Docosahexaenoic acid (DHA) exhibits various physiological processes such as regulating signal transduction pathways, neurotransmission, production of neurons and formation of myelin sheath around the axon. It is also associated with the membrane receptor function and synaptic plasticity. DHA supports membrane integrity, fluidity and organization. It is also found to be involved in neuroinflammation. DHA plays a vital role in the development and maturation of the brain.[2] 17(S)-HDHA (hydroxy docosahexaenoic acid) can serve as a precursor for specialized pro-resolving mediators (D-series).[3]

Verpackung

2 mL Amber Glass Sealed Ampule (900125E-100ug)
2 mL Amber Glass Sealed Ampule (900125E-500ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

FlameExclamation mark

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

55.4 °F - closed cup

Flammpunkt (°C)

13.0 °C - closed cup


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Analysenzertifikate (COA)

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Michael J Weiser et al.
Nutrients, 8(2), 99-99 (2016-02-24)
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid (PUFA) found in the brain and can affect neurological function by modulating signal transduction pathways, neurotransmission, neurogenesis, myelination, membrane receptor function, synaptic plasticity, neuroinflammation, membrane integrity and membrane organization.
Principles of Nutrigenetics and Nutrigenomics: Fundamentals of Individualized Nutrition, 460-460 (2019)
Miaomiao Ruan et al.
Journal of the neurological sciences, 396, 247-253 (2018-12-12)
Glioblastoma (GBM) is a typical malignant tumor, and there are no effective drugs capable of improving patient survival. Docosahexaenoic acid (DHA), a nutrient essential to animal health and neurodevelopment, exerts an anticancer effect in several types of cancer. However, the

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