850153P

18:1 PI(3,4)P2

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt), powder

• Synonym(e): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,4-bisphosphate] (ammonium salt); PIP2[3′,4′](18:1(9Z)/18:1(9Z))
• Empirische Formel (Hill-System): C₄₅H₉₄N₃O₁₉P₃
• CAS-Nummer: 799268-54-5
• Molekulargewicht: 1074.16
• MDL-Nummer: MFCD22416810
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 100 μg (with stopper and crimp cap (850153P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850153P-500ug))
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 850153P
• Lipid-Typ: phospholipids; cardiolipins
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+]

Beschreibung

Allgemeine Beschreibung

18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate)) is an ammonium salt of modified lipid.

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Anwendung

18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt)) has been used:

• in liposomes/supported lipid bilayer preparation[1]
• in liposome co-sedimentation[2]
• in the preparation of anionic phospholipid liposomes[3]

Biochem./physiol. Wirkung

PI(3,4)P2 can act as a lipid second messenger. In mast cells, PI(3,4)P2 plays a key role in protein kinase B (PKB) phosphorylation on Ser473 sites.[4]

Verpackung

2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-500ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids