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Sigma-Aldrich

25-Hydroxyvitamin D3 -Lösung

5 μg/mL in ethanol, 98% (CP)

Synonym(e):

25-Hydroxy-cholecalciferol -Lösung

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About This Item

Empirische Formel (Hill-System):
C27H44O2
CAS-Nummer:
19356-17-3
Molekulargewicht:
400.64
EG-Nummer:
200-578-6
MDL-Nummer:
MFCD00867077
UNSPSC-Code:
12352205
PubChem Substanz-ID:
329765369
NACRES:
NA.24

Assay

98% (CP)

Form

solution

Konzentration

5 μg/mL in ethanol

Methode(n)

mass spectrometry (MS): suitable

Farbe

colorless

Anwendung(en)

detection

Lagertemp.

−20°C

SMILES String

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1

InChIKey

JWUBBDSIWDLEOM-DTOXIADCSA-N

Angaben zum Gen

human ... VDR(7421)

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Allgemeine Beschreibung

25-Hydroxyvitamin D3 (calcifediol) is a prohormone produced via hydroxylation of vitamin D3 (cholecalciferol) in the liver. It is a precursor for the synthesis of calcitriol {1,25-dihydroxyvitamin D3 or [1,25(OH)2D3]}. It is also used as a biomarker to determine the status of vitamin D in the body.

Anwendung

This product may be used as an analytical standard.

Verpackung

1 mL in ampule

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Preisangaben

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

H-Sätze

H225,H319

Gefahreneinstufungen

Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

57.2 °F

Flammpunkt (°C)

14.0 °C

Analysenzertifikate (COA)

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Marina V Antunes et al.
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In view of the large variability on therapeutic response and the multiple factors associated to tamoxifen (TAM) metabolic activation, this study aimed to evaluate the effect of CYP2D6 and CYP3A4 phenotypes, drug interactions, and vitamin D exposure on TAM metabolism
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Molecular nutrition & food research, 59(8), 1513-1523 (2015-03-27)
The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated
Johanna Breuer et al.
Annals of neurology, 75(5), 739-758 (2014-04-29)
Environmental conditions (eg, latitude) play a critical role in the susceptibility and severity of many autoimmune disorders, including multiple sclerosis (MS). Here, we investigated the mechanisms underlying the beneficial effects of immune regulatory processes induced in the skin by moderate
Quantification of circulating 25-hydroxyvitamin D by liquid chromatography-tandem mass spectrometry
Vogeser M
The Journal of Steroid Biochemistry and Molecular Biology, 121(3-5), 565-573 (2010)
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