If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
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D1530
1α,25-Dihydroxyvitamin D3
≥99% (HPLC)
Synonym(e):
1α,25-Dihydroxycholecalciferol, Calcitriol
Größe auswählen
| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 μg | Warenkorb auf Verfügbarkeit prüfen | € 251,00 |
0.1 mg | Warenkorb auf Verfügbarkeit prüfen | € 1.290,00 |
Über diesen Artikel
Quality Segment
assay
≥99% (HPLC)
form
solid
technique(s)
HPLC: suitable
storage temp.
−20°C
SMILES string
[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)[C@H](C)CCCC(C)(C)O
InChI
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChI key
GMRQFYUYWCNGIN-NKMMMXOESA-N
Gene Information
human ... VDR(7421)
Application
- to study its effects on endothelial functions in high glucose-conditioned human umbilical vein endothelial cells (HUVECs)[1]
- to study the osteogenic effect of bone morphogenetic protein-2 (BMP2) in human bone marrow-derived mesenchymal stem cells (hMSCs)[2]
- in osteogenic differentiation medium for osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs)[3]
Biochem/physiol Actions
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - STOT RE 1
Lagerklasse
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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I can't see anything in the vial. How should Product D1530, 1´,25-Dihydroxyvitamin D3, look?
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D1530 is packaged by dispensing a solution into the vials, then drying them under inert gas. The product will be a thin film in the bottom of the vial, so it may appear to be empty by visual inspection.
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What is the best way to store stock solutions of Product D1530, 1?,25-Dihydroxyvitamin D3?
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1?,25-Dihydroxyvitamin D3 is both air and light sensitive, so should be stored under inert gas at either -20 or -70°C. The length of time a stock solution can be stored depends on how carefully air is excluded from the solution. If care is taken to exclude air, stock solutions may be stable indefinitely at -20°C.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How can I dissolve Product D1530, ?,25-Dihydroxyvitamin D3, for cell culture use?
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1?,25-Dihydroxyvitamin D3 is soluble in serveral organic solvents, including methanol, ethanol, ethyl acetate, and tetrahydrofuran. For cell culture use, a 10 μM stock solution can be prepared and diluted to the working concentration in cell culture media.
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