549169

5-Amino-3-(4-methylphenyl)-1-phenylpyrazol

97%

• Synonym(e): 3-(4-Methylphenyl)-1-phenyl-1H-pyrazol-5-amine
• Empirische Formel (Hill-System): C₁₆H₁₅N₃
• CAS-Nummer: 90012-40-1
• Molekulargewicht: 249.31
• MDL-Nummer: MFCD03427106
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24879063
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: solid
• mp (Schmelzpunkt): 173-176 °C (lit.)
• SMILES String: Cc1ccc(cc1)-c2cc(N)n(n2)-c3ccccc3
• InChI: 1S/C16H15N3/c1-12-7-9-13(10-8-12)15-11-16(17)19(18-15)14-5-3-2-4-6-14/h2-11H,17H2,1H3
• InChIKey: WMJZITXAXMNGCH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

5-Amino-3-(4-methylphenyl)-1-phenylpyrazole (3-(4-methylphenyl)-1-phenyl-1H-pyrazol-5-amine) belongs to a family of 5-aminopyrazole derivatives, which are bioactive agents.[1] They find a wide range of applications in the pharmaceutical and agrochemical industries. It can be prepared by refluxing a mixture of p-methyl-benzoylacetonitrile and phenylhydrazine in ethanol.[2]

Anwendung

5-Amino-3-(4-methylphenyl)-1-phenylpyrazole may be used in the preparation of N′-[4-formyl-3-(4-methylphenyl)-1-phenyl-1H-pyrazol-5-yl]-N,N-dimethylimidoformamide, an intermediate for preparing 5-amino-3-(4-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde.[2]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves