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531480

Sigma-Aldrich

Fmoc-Ala-OH

95%, for peptide synthesis

Synonym(e):

N-(Fluorenyl-9-methoxycarbonyl)-L-alanin, Fmoc-L-alanin

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€ 29,20
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€ 45,40
100 G
€ 113,00

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5 G
€ 29,20
25 G
€ 45,40
100 G
€ 113,00

About This Item

Empirische Formel (Hill-System):
C18H17NO4
CAS-Nummer:
Molekulargewicht:
311.33
Beilstein:
2225975
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.26

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Produktbezeichnung

Fmoc-Ala-OH, 95%

Assay

95%

Optische Aktivität

[α]20/D −18°, c = 1 in DMF

Eignung der Reaktion

reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis

mp (Schmelzpunkt)

147-153 °C (lit.)

Anwendung(en)

peptide synthesis

Funktionelle Gruppe

Fmoc
amine
carboxylic acid

Lagertemp.

2-8°C

SMILES String

C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1

InChIKey

QWXZOFZKSQXPDC-NSHDSACASA-N

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Allgemeine Beschreibung

Fmoc-Ala-OH also known as Fmoc-L-alanine, is a versatile reagent used in Fmoc solid-phase peptide synthesis.

Anwendung

Fmoc-Ala-OH is commonly used :
  • as a building block in the preparation of triazolopeptides , and azapeptides[1]
  • in the synthesis of bis-cationic porphyrin peptides using the standard Fmoc solid-phase synthesis[2]
  • to transform Mannich-adducts into α-halogenated amides without undergoing aziridination[3]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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