519324

1-(tert-Butyldimethylsilyloxy)-1-methoxyethen

97%

• Synonym(e): (1,1-Dimethylethyl)[(1-methoxyethenyl)oxy]dimethylsilane, (tert-Butyl)[(1-methoxyethenyl)oxy]dimethylsilane, 1-Methoxy-1-(tert-butyldimethylsiloxy)ethylene, 1-Methoxy-1-[(tert-butyldimethylsilyl)oxy]ethene, 1-Methoxy-1-[(tert-butyldimethylsilyl)oxy]ethylene, Ketene methyl t-butyldimethylsilyl acetal, Ketene tert-butyldimethylsilyl methyl acetal, tert-Butyl[(1-methoxyvinyl)oxy]dimethylsilane
• Lineare Formel: (CH₃)₃CSi(CH₃)₂OC(OCH₃)=CH₂
• CAS-Nummer: 77086-38-5
• Molekulargewicht: 188.34
• MDL-Nummer: MFCD02683524
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24874073
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Brechungsindex: n20/D 1.429 (lit.)
• bp: 62 °C/9 mmHg (lit.)
• Dichte: 0.863 g/mL at 25 °C (lit.)
• SMILES String: COC(=C)O[Si](C)(C)C(C)(C)C
• InChI: 1S/C9H20O2Si/c1-8(10-5)11-12(6,7)9(2,3)4/h1H2,2-7H3
• InChIKey: UVCCWXJGWMGZAB-UHFFFAOYSA-N

Beschreibung

Anwendung

1-(tert-Butyldimethylsilyloxy)-1-methoxyethene may be used in the following

• Synthesis of β-hydroxy esters via Mukaiyama Aldol reaction with heterocyclic aldehydes in the presence of Lewis acid.[1]
• Asymmetric Mukaiyama-Mannich reaction with isatin-derived ketimines to synthesize indolyl-β^3, 3-aminoacid esters.[2]
• Broadrup′s synthesis of epothilone D.[3]
• Preparation of N-benzylidene benzylamine N-oxide.[4]
• Synthesis of nitroso acetals.[5]

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Warning
• H-Sätze: H226
• Gefahreneinstufungen: Flam. Liq. 3
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 125.6 °F - closed cup
• Flammpunkt (°C): 52 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter