419656

N-Benzyl-2-nitro-1H-imidazol-1-acetamid

97%

• Synonym(e): 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide, Benzonidazol, N-Benzyl-2-nitroimidazol-1-yl-acetamide
• Empirische Formel (Hill-System): C₁₂H₁₂N₄O₃
• CAS-Nummer: 22994-85-0
• Molekulargewicht: 260.25
• MDL-Nummer: MFCD00243089
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24866267
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• mp (Schmelzpunkt): 189-192 °C (lit.)
• Löslichkeit: methanol: soluble 50 mg/mL, clear, colorless to yellow
• Funktionelle Gruppe: amide; nitro; phenyl
• SMILES String: [O-][N+](=O)c1nccn1CC(=O)NCc2ccccc2
• InChI: 1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
• InChIKey: CULUWZNBISUWAS-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

N-Benzyl-2-nitro-1H-imidazole-1-acetamide (Benznidazole) is a nitro-heterocyclic compound. It is widely employed drug for the treatment of Chagas disease. It exhibits three polymorphic forms..[1]

Anwendung

N-Benzyl-2-nitro-1H-imidazole-1-acetamide (Benznidazole) may be used as reference drug for the extraction of guaianolide from the aerial parts of Tanacetum parthenium and to evaluate its in vitro antiprotozoal activity.[2]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves