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Sigma-Aldrich

Barbitursäure Natriumsalz

≥97.0% (T)

Synonym(e):

Natriumbarbiturat

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About This Item

Empirische Formel (Hill-System):
C4H3N2NaO3
CAS-Nummer:
4390-16-3
Molekulargewicht:
150.07
Beilstein:
3748030
EG-Nummer:
224-507-3
MDL-Nummer:
MFCD00065377
UNSPSC-Code:
12352100
PubChem Substanz-ID:
57646950
NACRES:
NA.22

Assay

≥97.0% (T)

Löslichkeit

hot water: soluble 0.2 g/10 mL, clear, colorless

SMILES String

[Na+].[O-]C1=NC(=O)NC(=O)C1

InChI

1S/C4H4N2O3.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);/q;+1/p-1

InChIKey

MHQHHBYRYFICDV-UHFFFAOYSA-M

Verwandte Kategorien

Allgemeine Beschreibung

Sodium barbiturate is a white to light beige powder. It accelerates the propagation of metastatic prostate adenocarcinomas in rats and in tissue culture.

Anwendung

Sodium barbiturate has been used for quantification of thrombin in plasma. It has been used in the estimation of trypsin in duodenal contents. It was also used as a buffer to characterise the functions of two long-chain fatty acid CoA ligase genes (facl) in crude oil-degrading Geobacillus thermodenitrificans NG80-2.

Sonstige Hinweise

Kann Verkaufsbeschränkungen unterliegen.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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M Pollard et al.
Oncology, 34(3), 129-132 (1977-01-01)
Metastatic prostate adenocarcinomas, derived from aging germfree Wistar rats, have been propagated in rats and in tissue culture. A protocol has been developed and demonstrated for assay of treatments which retard or which accelerate the rate and extent of tumor
Simple method for estimating trypsin.
H S Wiggins
Gut, 8(4), 415-416 (1967-08-01)
F A Ofosu et al.
Blood, 64(3), 742-747 (1984-09-01)
Heparan with a low affinity for antithrombin III has previously been demonstrated to inhibit thrombin generation in both normal plasma and plasma depleted of antithrombin III. In addition, standard heparin and heparin with a low affinity for antithrombin III have
Thomas Gelbrich et al.
Acta crystallographica. Section C, Crystal structure communications, 66(Pt 1), o55-o58 (2010-01-06)
Both title structures exhibit essentially planar barbiturate rings. The crystal structure of enallylpropymal (5-allyl-5-isopropyl-1-methylbarbituric acid), C(11)H(16)N(2)O(3), is composed of centrosymmetric N-H...O hydrogen-bonded dimers, while 1,5-di(but-2-enyl)-5-ethylbarbituric acid, C(14)H(20)N(2)O(3), forms N-H...O hydrogen-bonded helical chains. Each of the ten known crystal structures of
Peter Ballard et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(12), 2165-2168 (2011-09-02)
Accurately predicting in vivo metabolic clearance from in vitro liver microsomes or hepatocytes requires a good understanding of the factors contributing to the prediction. Although much work has concentrated on deriving scaling factors and optimizing the metabolic stability techniques for
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