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PRKCA

protein kinase C, alpha

Synonyme:
AAG6, PKC-alpha, PKCA, PRKACA
Spezies:
Human PRKCA (5578), Mouse Prkca (18750), Rat Prkca (24680), Horse PRKCA (100063318), dog PRKCA (490904), Domestic Rabbit PRKCA (100037720), domestic cat PRKCA (101086433), sheep PRKCA (101110074), Zebrafish prkca (497384), chicken PRKCA (417430) ...Mehr
UniProtKB-ID:
P17252, B5BU22, Q15137, Q32M72, Q96RE4
Gen-ID:
  • Human(5578) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
  • Mouse(18750) protein kinase C, alpha
  • Rat(24680) protein kinase C, alpha
  • Horse(100063318) protein kinase C, alpha
  • dog(490904) protein kinase C, alpha
  • Domestic Rabbit(100037720) protein kinase C, alpha
  • domestic cat(101086433) protein kinase C, alpha
  • sheep(101110074) protein kinase C, alpha
  • Zebrafish(497384) protein kinase C, alpha
  • chicken(417430) protein kinase C, alpha
  • cow(282001) protein kinase C, alpha
  • domestic guinea pig(100302324) protein kinase C, alpha
  • domestic guinea pig(100713627) protein kinase C, alpha
  • naked mole-rat(101716044) protein kinase C, alpha

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Small Molecule - Activator

Produktnummer
Beschreibung
Spezies
20-133-M
PKC-Lipidaktivator, ,
Spezies
human

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
O1008
Oleinsäure, ≥99% (GC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB4502354
Anti-PKC α antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
western blot
SAB4200739
Anti-Protein kinase C antibody, Mouse monoclonal, clone MC5, purified from hybridoma cell culture,
Speziesreaktivität
bovine, chicken, fish, human, mouse, rabbit, rat
Anwendung
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
05-983
Anti-PKC Antibody (α, β, γ), clone M110, clone M110, Upstate®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB4502356
Anti-PKC-PAN antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
immunohistochemistry
western blot
HPA006563
Anti-PRKCA antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
S7049
D-Sphingosin, synthetic,
Spezies
rat
O6754
2-Acetyl-1-oleoyl-sn-glycerin, ≥97% (TLC), oil,
Spezies
human
K2015
K-252a, Ready Made Solution, from Nonomuraea longicatena, >98%,
Spezies
rat, human
K1639
K-252a, from Nonomuraea longicatena, ≥98% (HPLC),
Spezies
rat, human
C9911
(S)-(+)-Camptothecin, ≥90% (HPLC), powder,
Spezies
rat, mouse, human

Proteins

Produktnummer
Beschreibung
Spezies
14-484-M
PKCα Protein, active, 10 µg, Active, recombinant, full-length human PKCα, containing N-terminal His6 tag. For use in Kinase Assays.,
Spezies
human
P1782
Protein kinase Cα isozyme human, ≥70% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Spezies
human
SRP5251
PKC-α, active, GST tagged from Xanopus sp., PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies

esiRNA

Produktnummer
Beschreibung
Spezies
EMU080561
MISSION® esiRNA, targeting mouse Prkca,
Spezies
mouse
EHU050821
MISSION® esiRNA, targeting human PRKCA,
Spezies
human

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
20-131
PKC Substrate Cocktail, ,
Spezies
human
12-123
PKC Substrate Peptide, PKC Substrate Peptide primarily used in Kinase Assays.,
Spezies
human