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PARP1

poly (ADP-ribose) polymerase 1

Synonyme:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot
Anti-Poly-ADP-Ribose-Antikörper, Klon 10H, clone 10H, from mouse,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-cleaved PARP-1 Antibody, clone 2G13 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Benzamid, 99%,
Spezies
human
3-Aminobenzamid, ≥99% (TLC),
Spezies
mouse
Benzamid, purified by sublimation, ≥99.5%,
Spezies
human
6-(5H)-Phenanthridinon, technical grade,
Spezies
human
Nicotinamid, BioReagent, suitable for cell culture, suitable for insect cell culture,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
PARP-1 human, recombinant, expressed in E. coli,
Spezies
human
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Spezies
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Spezies
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PARP1,
Spezies
human
MISSION® esiRNA, targeting mouse Parp1,
Spezies
mouse