ESR1
estrogen receptor 1
Sinónimos:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Especie:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...Más
ID UniProtKB:
ID del gen:
- Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
- Mouse(13982) estrogen receptor 1 (alpha)
- Rat(24890) estrogen receptor 1
- domestic cat(552888) estrogen receptor 1
- dog(403640) estrogen receptor 1
- chicken(396099) estrogen receptor 1
- Thale Cress(837856) ethylene-responsive transcription factor ESR1
- Horse(791249) estrogen receptor 1
- Zebrafish(259252) estrogen receptor 1
- cow(407238) estrogen receptor 1
- Goat(100860768) estrogen receptor 1
- sheep(443228) estrogen receptor 1
- domestic guinea pig(100713276) estrogen receptor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Referencia del producto
Descripción
Especie
βDinucleótido de β-nicotinamida y adenina hydrate, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Especie
human
Small Molecule - Agonist
Referencia del producto
Descripción
Especie
17α-etinilestradiol, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Small Molecule - Allosteric Modulator
Referencia del producto
Descripción
Especie
Tamoxifeno, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Especie
human
Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
western blot
western blot
Anti-Estrogen-related Receptor α Antibody, Upstate®, from rabbit,
Reactividad de especies
hamster, human, mouse, rat
Aplicación
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
ChIPAb+ Estrogen Receptor α - ChIP Validated Antibody and Primer Set, ascites fluid, from mouse,
Reactividad de especies
human, mouse
Aplicación
ChIP
western blot
western blot
Anti-phospho-Estrogen Receptor alpha (Ser118) Antibody, clone NL44, rabbit monoclonal, clone NL44, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
Anti-Estradiol Antibody, clone 6E1, ascites fluid, clone 6E1, Chemicon®,
Reactividad de especies
human
Aplicación
ELISA
Small Molecule - Inhibitor
Small Molecule - Ligand
Referencia del producto
Descripción
Especie
Small Molecule - Mixed Agonist/Antagonist
Referencia del producto
Descripción
Especie
Proteins
Referencia del producto
Descripción
Especie
Estrogen Receptor-α human, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Especie
human
esiRNA
Referencia del producto
Descripción
Especie