M1629

Medroxyprogesterone 17-acetate

≥97% (HPLC)

• Sinónimos: 17α-Acetoxy-6α-methylprogesterone, 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-acetate, 6α-Methyl-17α-acetoxyprogesterone, 6α-Methyl-17α-hydroxyprogesterone acetate
• Fórmula empírica (notación de Hill): C₂₄H₃₄O₄
• Número de CAS: 71-58-9
• Peso molecular: 386.52
• Beilstein/REAXYS Number: 2066112
• EC Number: 200-757-9
• MDL number: MFCD00010483
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896674
• NACRES: NA.77

Propiedades

• biological source: synthetic (organic)
• Quality Level: 100
• sterility: non-sterile
• assay: ≥97% (HPLC)
• form: powder
• mp: 206-207 °C (lit.)
• solubility: chloroform: 350 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O
• InChI: 1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
• InChI key: PSGAAPLEWMOORI-PEINSRQWSA-N
• Gene Information: human ... AR(367) , ESR1(2099) , ESRRA(2101) , NR3C1(2908) , NR3C2(4306) , PGR(5241) ; rat ... Ar(24208)

Descripción

Biochem/physiol Actions

Medroxyprogesterone 17-acetate (MPA) is a synthetic progestin used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis. It is a more potent progestin that the nonacetylated form.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• pictograms: GHS08
• signalword: Warning
• hcodes: H351,H413
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 4 - Carc. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges