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Anti-Caspase-8 antibody produced in rabbit

Name: Anti-Caspase-8 antibody produced in rabbit
Brand: SIGMA
Price: 584 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-FLICE, Anti-MACH, Anti-Mch5

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Pack Size	SKU	Availability	Price
100 μg		Check Cart for Availability	$584.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01633094

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA, ICC, IF, IHC, WB

Citations:

$584.00

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A recombinant, preservative-free antibody is available for your target. Try ZRB1426

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 55 kDa

species reactivity

human, mouse, rat

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

NP_001219

UniProt accession no.

Q14790

shipped in

dry ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CASP8(841)

Description

Immunogen

Caspase-8 antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human Caspase-8 isoform A.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500404.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB4503321	C7729	HPA001302
Sigma-Aldrich SAB3500404 Anti-Caspase-8 antibody produced in rabbit	Sigma-Aldrich SAB4503321 Anti-CASP8 (Cleaved-Asp³⁸⁴), C-Terminal antibody produced in rabbit	Sigma-Aldrich C7729 Anti-Caspase 9 antibody produced in rabbit	Sigma-Aldrich HPA001302 Anti-CASP8 antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level -	Quality Level 200	Quality Level 100
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
technique(s) ELISA: suitable, immunofluorescence: suitable, western blot: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable	technique(s) ELISA: 1:40000, western blot: 1:500-1:1000	technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:40 using microwave-treated tissue sections of human and rat heart, immunoprecipitation (IP): 10 μg using HeLa mitochondrial RIPA lysate (500 μg), microarray: suitable, western blot: 1:300 using whole extract of human Jurkat cells	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:200-1:500
Gene Information human ... CASP8(841)	Gene Information human ... CASP8(841)	Gene Information human ... CASP9(842) rat ... Casp9(58918)	Gene Information human ... CASP8(841)

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Polyisoprenylated Cysteinyl Amide Inhibitors Deplete K-Ras and Induce Caspase-dependent Apoptosis in Lung Cancer Cells.

Augustine T Nkembo et al.

Current cancer drug targets, 19(10), 838-851 (2019-03-28)

Non-small cell lung cancers (NSCLC) harboring mutation-induced dysregulation of Ras signaling present some of the most difficult-to-manage cases, since directly targeting the constitutively active mutant Ras proteins has not resulted in clinically useful drugs. Therefore, modulating Ras activity for targeted

Do arachidonic acid metabolites affect apoptosis in bovine endometrial cells with silenced PPAR genes?

A A Szczepańska et al.

Prostaglandins & other lipid mediators, 143, 106336-106336 (2019-05-22)

Peroxisome proliferator-activated receptors (PPARs) are expressed in bovine uterus, and their agonists are arachidonic acid (AA) metabolites. We hypothesised that silencing of PPAR genes in bovine endometrial stromal cells (ESC) would change the intracellular signalling through PPAR and affect apoptosis

Global Trade Item Number

SKU	GTIN
SBP3500404-0.05MG	04061832161525
SAB3500404-100UG	04061832179551

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